5-Hydroxy-33-tert-butyldimethylsilyloxy-iso-FK-506

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Names

[ CAS No. ]:
134556-79-9

[ Name ]:
5-Hydroxy-33-tert-butyldimethylsilyloxy-iso-FK-506

Chemical & Physical Properties

[ Molecular Formula ]:
C50H85NO10Si

[ Molecular Weight ]:
888.29600

[ Exact Mass ]:
887.59400

[ PSA ]:
152.06000

[ LogP ]:
8.36510

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 33-O-tert-butyldimethylsilyl-22(S)-dihydro-FK-506
  • N,N-Carbonyldiimidazole
  • Tacrolimus
  • 33-O-tert.butyldimethylsilyl-FK-506
  • tert-Butyldimethylsilyl chloride

DownStream

  • Iso-FK-506 (iso-Tacrolimus)

Related Compounds

  • 22-Hydroxy-33-O-tert-butyldimethylsilyloxy-27-O-triMethylsilyl-iso-FK-506
  • 5-(TERT-BUTYLDIMETHYLSILYLOXY)-1-PENTANOL
  • 5-(tert-butyldimethylsilyloxy)pent-1-yl 3-amino-5-(trifluoromethyl)benzoate
  • 5-tert-butyldimethylsilyloxy-4-oxo-4H-pyran-2-carbaldehyde
  • 5-(tert-butyldimethylsilyloxy)pent-1-yl 5-(trifluoromethyl)-3-nitrobenzoate
  • 5-(tert-butyldimethylsilyloxy) isophthalaldehyde
  • (4As,8aR)-4a,8a-dimethoxy-1,2,3,4,5,6,7,8-octahydroisoquinoline;hydrochloride
  • Methyl (2R,4R)-2-cyclopropylpiperidine-4-carboxylate;hydrochloride
  • Methyl (3R,4R)-3-aminopiperidine-4-carboxylate;dihydrochloride
  • 1,1,1-Trifluoro-N-((11bS)-4-(((11bS)-4-oxido-2,6-bis(2,4,6-triethylphenyl)dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-yl)amino)-2,6-bis(2,4,6-triethylphenyl)-4l5-dinaphtho[2,1-d:1',2'-f][1,3,2]dioxaphosphepin-4-ylidene)methanesulfonamide
  • Methanone, (5-chloro-2-pyridinyl)[3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-
  • Tert-butyl (2-((5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidin-2-yl)amino)ethyl)carbamate
  • 4-Methyl-3-(methylsulfanyl)cyclohexan-1-one
  • (E)-4-(Dimethylamino)-N-[2-[2-(trifluoromethyl)-1H-indol-3-yl]ethyl]but-2-enamide
  • tert-butyl N-(3-cyano-6-methylpyridin-2-yl)carbamate
  • 2,5-dichloro-4-methoxy-N-[2-(propan-2-yl)phenyl]benzene-1-sulfonamide
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