tungsten

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Names

[ CAS No. ]:
13472-45-2

[ Name ]:
tungsten

[Synonym ]:
EINECS 231-143-9
Sodium tungstate
TUNGSTEN
MFCD00011461

Chemical & Physical Properties

[ Density]:
3.25

[ Boiling Point ]:
5660 °C(lit.)

[ Melting Point ]:
698ºC

[ Molecular Formula ]:
W

[ Molecular Weight ]:
183.84000

[ Exact Mass ]:
183.95100

[ Appearance of Characters ]:
wire

[ Water Solubility ]:
H2O: soluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YO7875000
CHEMICAL NAME :
Tungstic acid, disodium salt
CAS REGISTRY NUMBER :
13472-45-2
LAST UPDATED :
199712
DATA ITEMS CITED :
34
MOLECULAR FORMULA :
O4-W.2Na
MOLECULAR WEIGHT :
293.83
WISWESSER LINE NOTATION :
NA2 WO-O4

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1190 mg/kg
TOXIC EFFECTS :
Behavioral - excitement Behavioral - muscle weakness
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
240 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
240 mg/kg
TOXIC EFFECTS :
Autonomic Nervous System - other (direct) parasympathomimetic Behavioral - excitement Behavioral - muscle weakness
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Mammal - dog
DOSE/DURATION :
140 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - cat
DOSE/DURATION :
139 mg/kg
TOXIC EFFECTS :
Vascular - BP lowering not characterized in autonomic section Lungs, Thorax, or Respiration - respiratory depression
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
875 mg/kg
TOXIC EFFECTS :
Behavioral - excitement Behavioral - muscle weakness
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
78 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
105 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - food intake (animal) Gastrointestinal - hypermotility, diarrhea
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
1152 mg/kg
TOXIC EFFECTS :
Behavioral - excitement Behavioral - muscle weakness
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
810 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
106 mg/kg/30W-I
TOXIC EFFECTS :
Behavioral - alteration of classical conditioning
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
504 ug/m3/24H/17W-C
TOXIC EFFECTS :
Blood - other changes Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Metabolism (Intermediary) - other proteins
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
1214 mg/kg/35W-I
TOXIC EFFECTS :
Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases
TYPE OF TEST :
TCLo - Lowest published toxic concentration
ROUTE OF EXPOSURE :
Inhalation
DOSE :
504 ug/m3/24H
SEX/DURATION :
male 17 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Paternal Effects - spermatogenesis (incl. genetic material, sperm morphology, motility, and count)

MUTATION DATA

TYPE OF TEST :
Sex chromosome loss and nondisjunction
TEST SYSTEM :
Yeast - Saccharomyces cerevisiae
REFERENCE :
MUTAEX Mutagenesis. (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1986- Volume(issue)/page/year: 1,21,1986 *** REVIEWS *** ACGIH TLV-TWA 5 mg(W)/m3; STEL 10 mg(W)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: TLV/BEI,1997 *** U.S. STANDARDS AND REGULATIONS *** MSHA STANDARD-air:TWA 5 mg(W)/m3 DTLVS* The Threshold Limit Values (TLVs) and Biological Exposure Indices (BEIs) booklet issues by American Conference of Governmental Industrial Hygienists (ACGIH), Cincinnati, OH, 1996 Volume(issue)/page/year: 3,272,1971 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-AUSTRALIA:TWA 5 mg(W)/m3;STEL 10 mg(W)/m3 JAN 1993 OEL-BELGIUM:TWA 5 mg(W)/m3;STEL 10 mg(W)/m3 JAN 1993 OEL-DENMARK:TWA 5 mg(W)/m3 JAN 1993 OEL-FINLAND:TWA 5 mg(W)/m3 JAN 1993 OEL-THE NETHERLANDS:TWA 5 mg(W)/m3 JAN 1993 OEL-THE PHILIPPINES:TWA 1 mg(W)/m3 JAN 1993 OEL-SWEDEN:TWA 5 mg(W)/m3 JAN 1993 OEL-SWITZERLAND:TWA 5 mg(W)/m3 JAN 1993 OEL-UNITED KINGDOM:TWA 5 mg(W)/m3;STEL 10 mg(W)/m3 JAN 1993 OEL IN BULGARIA, COLOMBIA, JORDAN, KOREA check ACGIH TLV OEL IN NEW ZEALAND, SINGAPORE, VIETNAM check ACGIH TLV *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH RECOMMENDED EXPOSURE LEVEL (REL) : NIOSH REL TO TUNGSTEN, soluble-air:10H TWA 1 mg(W)/m3;STEL 3 mg/m3 REFERENCE : NIOSH* National Institute for Occupational Safety and Health, U.S. Dept. of Health, Education, and Welfare, Reports and Memoranda. Volume(issue)/page/year: DHHS #92-100,1992 NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 84829 No. of Facilities: 895 (estimated) No. of Industries: 13 No. of Occupations: 20 No. of Employees: 15470 (estimated) No. of Female Employees: 8875 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P337 + P313

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
36/38

[ Safety Phrases ]:
6-26-36

[ RIDADR ]:
UN 3089 4.1/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
YO7175000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2841802000

Customs

[ HS Code ]: 2841802000

Articles

Tungsten-enhanced growth of Methanosphaera stadtmanae.

BMC Res. Notes 5 , 238, (2012)

The methanogenic Archaea Methanosphaera stadtmanae has been detected in the human gut microbiota by both culture and culture-independent methods. Its growth reaches an exponential phase after 5 to 7-d...

Efficient degradation of methabenzthiazuron photoinduced by decatungstate anion in water: kinetics and mechanistic studies.

Chemosphere 85(4) , 558-64, (2011)

This study concerns the elimination of methabenzthiazuron (MBTU) photocatalysed by sodium decatungstate salts W10O32(4-)·(DTA) in aqueous solution under irradiation at 365 nm. Ninety percentage of MBT...

The potential reproductive, neurobehavioral and systemic effects of soluble sodium tungstate exposure in Sprague-Dawley rats.

Toxicol. Appl. Pharmacol. 254(2) , 133-7, (2011)

The debate on tungsten (W) is fostered by its continuous usage in military munitions. Reports demonstrate W solubilizes in soil and can migrate into drinking water supplies and, therefore, is a potent...


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