Sodium 5'-O-(hydroxyphosphinato)adenosine

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Names

[ Name ]:
Sodium 5'-O-(hydroxyphosphinato)adenosine

[Synonym ]:
EINECS 224-961-2
5'-Adenylic acid, sodium salt (1:1)
MFCD00065023
Sodium AMP
Sodium 5'-O-(hydroxyphosphinato)adenosine
Sodium adenosine-5'-monophosphate

Chemical & Physical Properties

[ Boiling Point ]:
798.5ºC at 760mmHg

[ Molecular Formula ]:
C₁₀H₁₃N₅NaO₇P

[ Molecular Weight ]:
369.203

[ Flash Point ]:
436.7ºC

[ Exact Mass ]:
369.045044

[ PSA ]:
198.71000

[ Vapour Pressure ]:
6.7E-27mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: AU7490000

CHEMICAL NAME :: 5'-Adenylic acid, sodium salt

CAS REGISTRY NUMBER :: 13474-03-8

LAST UPDATED :: 199504

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C10-H14-N5-O7-P.xNa

MOLECULAR WEIGHT :: 508.19

WISWESSER LINE NOTATION :: T56 BN DN FN HNJ IZ D- BT5OTJ CQ DQ E1OPQQO &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2049 mg/kg

TOXIC EFFECTS :: Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia

REFERENCE :: OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 4,689,1970

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,24,1957 *** REVIEWS *** TOXICOLOGY REVIEW ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 7,24,1957 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X9129 No. of Facilities: 215 (estimated) No. of Industries: 2 No. of Occupations: 3 No. of Employees: 3640 (estimated) No. of Female Employees: 2470 (estimated)

Safety Information

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S22;S24/25

Related Compounds

Potassium 5'-O-(hydroxyphosphinato)adenosine
Sodium 5'-O-phosphonatoinosine hydrate (2:1:1)
Sodium 5'-O-phosphonatouridine hydrate (2:1:1)
Sodium 5'-O-phosphonatoinosine hydrate (2:1:1)
Adenosine-5'-diphosphatedisodiumsalt
2'-Deoxyadenosine-5'-diphosphate disodium salt
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1-[(5-methylthiophen-2-yl)sulfonyl]piperidine-3-carboxylate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 3-[(3-chlorophenyl)methoxy]benzoate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 3-(2-oxo-3-propyl-2,3-dihydro-1H-1,3-benzodiazol-1-yl)propanoate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-{[4-(propan-2-yloxy)phenyl]sulfamoyl}acetate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-[4-(pyridin-2-yloxy)phenoxy]acetate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 2-[(4-chlorophenoxy)methyl]-4-methyl-1,3-thiazole-5-carboxylate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 4-methoxy-2-(methoxymethyl)-5-methylthieno[2,3-d]pyrimidine-6-carboxylate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1-[3-(trifluoromethyl)phenyl]cyclopentane-1-carboxylate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1-(6-ethoxypyridazin-3-yl)-5-methyl-1H-pyrazole-4-carboxylate
1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl 1-benzyl-3-(3,4-dimethoxyphenyl)-1H-pyrazole-4-carboxylate

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