1-[[2-(diethylamino)-6,7-dimethoxyquinazolin-4-yl]amino]-3-methylurea

Names

[ CAS No. ]:
134749-40-9

[ Name ]:
1-[[2-(diethylamino)-6,7-dimethoxyquinazolin-4-yl]amino]-3-methylurea

Chemical & Physical Properties

[ Density]:
1.245g/cm3

[ Molecular Formula ]:
C16H24N6O3

[ Molecular Weight ]:
348.40000

[ Exact Mass ]:
348.19100

[ PSA ]:
104.13000

[ LogP ]:
2.41740

[ Index of Refraction ]:
1.623

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
MV1576800
CHEMICAL NAME :
Hydrazinecarboxamide, 2-(2-(diethylamino)-6,7-dimethoxy-4-quinazolinyl)-N-m ethyl-, hydrate
CAS REGISTRY NUMBER :
134749-40-9
LAST UPDATED :
199212
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H24-N6-O3.H2-O
MOLECULAR WEIGHT :
366.48

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
191 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 25,15,1991

Synthetic Route

Click to get detail synthetic route

Related Compounds

  • 3-(5-Nitrothiophen-2-yl)butan-1-amine
  • [(4-Aminophenyl)(thiomorpholin-4-yl)imino-lambda6-sulfanyl]one
  • [2-(1,3-Oxazol-5-yl)propyl](propyl)amine
  • lithium;(2R)-2-[[1-(benzenesulfonyl)pyrrolo[2,3-b]pyridin-2-yl]methyl]pyrrolidine-1-sulfonate
  • Glycine, N-methyl-N-[(phenylamino)thioxomethyl]-L-leucyl-L-valyl-N-methyl-L-leucyl-L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-(2S,3R,4R,6E)-3-(acetyloxy)-4-methyl-2-(methylamino)-6-octenoyl-(2S)-2-aminobutanoyl-N-methyl-, methyl ester
  • 3-chloro-5-[(1,5-dimethyl-1H-pyrazol-3-yl)methyl]-1,2,3,6-tetrahydropyridine
  • (E)-but-2-enedioic acid;N-(4-imidazol-1-ylbutyl)-1H-benzo[cd]indol-2-imine
  • 3-Oxazolidinepentanoic acid,-[(S)-[(4-fluorophenyl)amino][4-(2-propen-1-yloxy)phenyl]methyl]-,2-dioxo-4-phenyl-, phenylmethyl ester, (R,4S)-
  • 4-O-tert-butyl 1-O-[(3R,5R,8R,9S,10S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-5-[(2-methylpropan-2-yl)oxy]-5-oxopentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-3-yl] (2S)-2-(9H-fluoren-9-ylmethoxycarbonylamino)butanedioate
  • [1,1'-Biphenyl]-4-propanoic acid,-(acetylamino)-, (R)-, compd. with (S)--methylbenzenemethanamine (1:1)