Ethane,1,2-bis(chloromethoxy)-

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Names

[ CAS No. ]:
13483-18-6

[ Name ]:
Ethane,1,2-bis(chloromethoxy)-

[Synonym ]:
1,2-Bis-chlormethoxy-aethan
ethylene glycol bisdichloromethyl ether
EINECS 236-791-6
Ethane,1,2-bis(chloromethoxy)
1,2-bis[(chloromethyl)oxy]ethane
1,6-dichloro-2,5-dioxahexane
1,2-bis-chloromethoxy-ethane
Bis-1,2-(chloromethoxy)ethane
Ethylene glycol bis(chloromethyl) ether
1,2-di(chloromethoxy)ethane

Chemical & Physical Properties

[ Density]:
1.222g/cm3

[ Boiling Point ]:
186.9ºC at 760mmHg

[ Molecular Formula ]:
C4H8Cl2O2

[ Molecular Weight ]:
159.01100

[ Flash Point ]:
71.6ºC

[ Exact Mass ]:
157.99000

[ PSA ]:
18.46000

[ LogP ]:
1.41220

[ Vapour Pressure ]:
0.89mmHg at 25°C

[ Index of Refraction ]:
1.432

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
KH5450000
CHEMICAL NAME :
Ethane, 1,2-bis(chloromethoxy)-
CAS REGISTRY NUMBER :
13483-18-6
BEILSTEIN REFERENCE NO. :
1735727
LAST UPDATED :
199701
DATA ITEMS CITED :
7
MOLECULAR FORMULA :
C4-H8-Cl2-O2
MOLECULAR WEIGHT :
159.02
WISWESSER LINE NOTATION :
G1O2O1G

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
8640 mg/kg/72W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
940 mg/kg/78W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
970 mg/kg/81W-I
TOXIC EFFECTS :
Tumorigenic - neoplastic by RTECS criteria Tumorigenic - tumors at site of application
REFERENCE :
CNREA8 Cancer Research. (Public Ledger Building, Suit 816, 6th & Chestnut Sts., Philadelphia, PA 19106) V.1- 1941- Volume(issue)/page/year: 35,2553,1975 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,31,1977 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 15,31,1977 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987

Safety Information

[ HS Code ]:
2909199090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Formaldehyde
  • Ethylene glycol
  • trioxane
  • Hydrochloric acid

DownStream

  • Butane,1,1'-[methylenebis(oxy)]bis-
  • 1,2-bis-butoxymethoxy-ethane
  • bis-(2-butoxymethoxy-ethyl) ether
  • (E)-1-[1-methyl-3-[[(E)-2-[[3-methyl-2-[(E)-oxidoiminomethyl]-2H-imidazol-1-yl]methoxy]ethenoxy]methyl]-2H-imidazol-2-yl]-N-oxidomethanimine,dichloride
  • 2-(acetyloxymethoxy)ethoxymethyl acetate
  • 1-[butyl-[2-(dibutylphosphorylmethoxy)ethoxymethyl]phosphoryl]butane

Customs

[ HS Code ]: 2909199090

[ Summary ]:
2909199090. other acyclic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

Related Compounds

  • ethane-1,2-bis-(thioglyoxime)
  • Ethane,1,2-bis(isopropylsulfonyl)- (7CI,8CI)
  • Ethane,1,2-bis(ethylthio)-
  • Ethane,1,2-bis(p-tolylsulfinyl)- (7CI,8CI)
  • Ethane, 1,2-bis(5-phenyl-1H-1,2,4-triazol-3-yl)-
  • ethane-1,2-bis(P-phosphinylacetic acid)