o-Anisaldehyde

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Names

[ CAS No. ]:
135-02-4

[ Name ]:
o-Anisaldehyde

[Synonym ]:
Benzaldehyde, 2-methoxy-
Salicylaldehyde Methyl Ether
o-Anisaldehyde
MFCD00003308
EINECS 205-171-7
2-Methoxybenzolcarbaldehyd
2-methoxybenzaldehyde
o-Anisaldehyde,Salicylaldehyde methyl ether

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
243.5±0.0 °C at 760 mmHg

[ Melting Point ]:
34-40 °C(lit.)

[ Molecular Formula ]:
C₈H₈O₂

[ Molecular Weight ]:
136.148

[ Flash Point ]:
117.8±0.0 °C

[ Exact Mass ]:
136.052429

[ PSA ]:
26.30000

[ LogP ]:
1.72

[ Vapour Pressure ]:
0.0±0.4 mmHg at 25°C

[ Index of Refraction ]:
1.547

[ Water Solubility ]:
insoluble

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: BZ2610000

CHEMICAL NAME :: o-Anisaldehyde

CAS REGISTRY NUMBER :: 135-02-4

BEILSTEIN REFERENCE NO. :: 0606301

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C8-H8-O2

MOLECULAR WEIGHT :: 136.16

WISWESSER LINE NOTATION :: VHR BO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2400 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - lacrimation Behavioral - somnolence (general depressed activity) Gastrointestinal - changes in structure or function of salivary glands

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: >5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Sister chromatid exchange

TEST SYSTEM :: Human Lymphocyte

DOSE/DURATION :: 125 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 206,17,1988

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ RTECS ]:
BZ2610000

[ Packaging Group ]:
I; II; III

[ HS Code ]:
29124900

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

iodoanisole
carbon monoxide
[acetyloxy-(2-methoxyphenyl)methyl] acetate
2-(2-methoxyphenyl)-1,3-dithiane
o-methoxybenzyl alcohol
bromoanisole
2-Methoxybenzonitrile
o-Methoxycinnamaldehyde
2-methoxybenzaldehyde semicarbazone
Salicylaldehyde

DownStream

3-(2-Methoxyphenyl)-1-propanol
1-(2-methoxyphenyl)-N-propylmethanimine
1,3-bis(2-methoxyphenyl)prop-2-en-1-one
Methyl 2-methoxybenzoate
Benzofuran-2-carboxylic acid
4-chloro-1-(2-methoxyphenyl)butan-1-one
Isoquinolin-8-ol
O,P-METHOXYCHLOR
5-Iodo-2-methoxybenzaldehyde
Methyl 3-(2-methoxyphenyl)-2-phenylacrylate

Customs

[ HS Code ]: 2912499000

[ Summary ]:
2912499000. other aldehyde-ethers, aldehyde-phenols and aldehydes with other oxygen function. VAT:17.0%. Tax rebate rate:9.0%. . MFN tariff:5.5%. General tariff:30.0%

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