CGS-12066 maleate

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Names

[ CAS No. ]:
1350965-83-1

[ Name ]:
CGS-12066 maleate

[Synonym ]:
7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo-[1,2-a]quinoxaline maleate salt

Chemical & Physical Properties

[ Molecular Formula ]:
C21H21F3N4O4

[ Molecular Weight ]:
450.41

[ Exact Mass ]:
450.15100

[ PSA ]:
98.38000

[ LogP ]:
2.97280

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Functional consequence of the MET-T1010I polymorphism in breast cancer.

Oncotarget 6(5) , 2604-14, (2015)

Major breast cancer predisposition genes, only account for approximately 30% of high-risk breast cancer families and only explain 15% of breast cancer familial relative risk. The HGF growth factor rec...

Cell-cell adhesions and cell contractility are upregulated upon desmosome disruption.

PLoS ONE 9(7) , e101824, (2014)

Desmosomes are perturbed in a number of disease states - including genetic disorders, autoimmune and bacterial diseases. Here, we report unexpected changes in other cell-cell adhesion structures upon ...

MYC is a critical target of FBXW7.

Oncotarget 6(5) , 3292-305, (2015)

MYC deregulation is a driver of many human cancers. Altering the balance of MYC protein levels at the level of transcription, protein stability, or turnover is sufficient to transform cells to a tumor...


More Articles


Related Compounds

  • (2S)-2-[(2S)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanamido]-4-hydroxybutanoic acid
  • 4-{[3-bromo-4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)phenyl]formamido}pentanoic acid
  • 2-{4-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)pentanoyl]-1,4-diazepan-1-yl}acetic acid
  • 3-({[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclobutyl]formamido}methyl)-5-methylhexanoic acid
  • 4-{2-[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclohexyl]acetamido}-2-methylbutanoic acid
  • 2-({5-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]furan-2-yl}formamido)-4,4-difluorobutanoic acid
  • 3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-(4-methanesulfonylpiperidin-1-yl)-4-oxobutanoic acid
  • 1-{2-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]acetyl}-2-methylpyrrolidine-3-carboxylic acid
  • (2S,4R)-1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1-methylcyclopentanecarbonyl]-4-hydroxypyrrolidine-2-carboxylic acid
  • 3-({2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]pyridin-4-yl}formamido)-2,2-difluoropropanoic acid
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