CGS-12066 maleate

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Names

[ CAS No. ]:
1350965-83-1

[ Name ]:
CGS-12066 maleate

[Synonym ]:
7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo-[1,2-a]quinoxaline maleate salt

Chemical & Physical Properties

[ Molecular Formula ]:
C21H21F3N4O4

[ Molecular Weight ]:
450.41

[ Exact Mass ]:
450.15100

[ PSA ]:
98.38000

[ LogP ]:
2.97280

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Functional consequence of the MET-T1010I polymorphism in breast cancer.

Oncotarget 6(5) , 2604-14, (2015)

Major breast cancer predisposition genes, only account for approximately 30% of high-risk breast cancer families and only explain 15% of breast cancer familial relative risk. The HGF growth factor rec...

Cell-cell adhesions and cell contractility are upregulated upon desmosome disruption.

PLoS ONE 9(7) , e101824, (2014)

Desmosomes are perturbed in a number of disease states - including genetic disorders, autoimmune and bacterial diseases. Here, we report unexpected changes in other cell-cell adhesion structures upon ...

MYC is a critical target of FBXW7.

Oncotarget 6(5) , 3292-305, (2015)

MYC deregulation is a driver of many human cancers. Altering the balance of MYC protein levels at the level of transcription, protein stability, or turnover is sufficient to transform cells to a tumor...


More Articles


Related Compounds

  • 4-({1-[2-(Methylsulfanyl)pyrimidin-4-yl]piperidin-4-yl}methoxy)pyridine-2-carboxamide
  • 4-(6-chloroquinoxalin-2-yl)-N-methylmorpholine-2-carboxamide
  • 1-(5-Chloro-4-methyl-1,3-benzothiazol-2-yl)pyrrolidin-3-ol
  • N-methyl-4-(quinoxalin-2-yl)morpholine-2-carboxamide
  • 2-[4-(Difluoromethyl)piperidin-1-yl]quinoline-3-carbonitrile
  • N-tert-butyl-1-(1-phenylethyl)piperidine-3-carboxamide
  • 4-(6-chloro-1,3-benzothiazol-2-yl)-N-methylmorpholine-2-carboxamide
  • 4-(6-bromoquinazolin-4-yl)-N-methylmorpholine-2-carboxamide
  • 4-(4,6-dimethyl-1,3-benzothiazol-2-yl)-N-methylmorpholine-2-carboxamide
  • 4-(6-bromoquinazolin-2-yl)-N-methylmorpholine-2-carboxamide
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