3,5-Di(tert-butyldimethylsilyl) Rosuvastatin

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Names

[ CAS No. ]:
1353050-10-8

[ Name ]:
3,5-Di(tert-butyldimethylsilyl) Rosuvastatin

[Synonym ]:
(E,3S,5R)-3,5-bis[[tert-butyl(dimethyl)silyl]oxy]-7-[4-(4-fluorophenyl)-2-[methyl(methylsulfonyl)amino]-6-propan-2-ylpyrimidin-5-yl]hept-6-enoic acid

Chemical & Physical Properties

[ Molecular Formula ]:
C34H56FN3O6SSi2

[ Molecular Weight ]:
710.05900

[ Exact Mass ]:
709.34100

[ PSA ]:
127.30000

[ LogP ]:
9.54150

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (3R,5S,E)-methyl 3,5-bis(tert-butyldimethylsilyloxy)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)hept-6-enoate
  • Rosuvastatin methyl ester

DownStream

Related Compounds

  • Nintedanib Ethanesulfonate Salt
  • 3,5-Di-O-(tert-butyldimethylsilyl)-2-deoxy-D-ribonolactone
  • 3,5-di(tert-butyl)-6-oxo-6H-pyran-2-carboxylic acid
  • 3,5-Di-Tert-Butylbenzyl Alcohol
  • 3,5-di-tert-butylsalicylic acid, zinc salt
  • 3,5-di-tert-butyl-2-hydroxybenzamide
  • 2-(1,1-Dimethylethyl)-6-methyl-4-pyridinecarbonitrile
  • (1R,3R,4R)-4-Aminocyclohexane-1,3-diol
  • 1-Methyl-N-(3-methylphenyl)-1H-pyrazol-4-amine
  • 3-Bromo-2-(hydrazinylmethyl)pyridine
  • 1-Bromo-2,3-difluoro-6-(difluoromethoxy)benzene
  • 1-Iodo-2-propoxycyclopentane
  • tert-butyl (R)-2-(2,2-dimethyl-5-oxo-1,3-dioxolan-4-yl)acetate
  • (3-Chloro-6-methoxy-1-benzothiophen-2-yl)-(2,6-dimethylphenyl)methanone
  • (2-Chloro-4-fluorophenyl)(3-chloro-6-methoxybenzo[b]thien-2-yl)methanone
  • 5-Fluoro-3-methylthiophene-2-carboxylic acid
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