(Tyr5,D-Trp6.8.9,Lys-NH2¹⁰)-Neurokinin A (4-10)

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Names

[ CAS No. ]:
135306-85-3

[ Name ]:
(Tyr5,D-Trp6.8.9,Lys-NH2¹⁰)-Neurokinin A (4-10)

[Synonym ]:
L-Asp-L-Tyr-D-Trp-L-Val-D-Trp-D-Trp-L-Lys-NH2
NK2 TACHYKININ RECEPT
M.W. 1081.24 C57H68N12O10
(TYR5,D-TRP6·8·9,LYS-NH210)-NEUROKININ A (4-10)
Men 10376

Chemical & Physical Properties

[ Density]:
1.361 g/cm3

[ Boiling Point ]:
1555.4ºC at 760 mmHg

[ Molecular Formula ]:
C57H68N12O10

[ Molecular Weight ]:
1081.22000

[ Flash Point ]:
894.5ºC

[ Exact Mass ]:
1080.52000

[ PSA ]:
374.63000

[ LogP ]:
6.53410

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.672

[ Storage condition ]:
-20°C

[ Water Solubility ]:
Insuluble (2.3E-3 g/L) (25 ºC)

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
N

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3.0

Articles

Effects of substance P on identified neurons of the rat dorsal motor nucleus of the vagus.

Am. J. Physiol. Gastrointest. Liver Physiol. 281(1) , G164-72, (2001)

Previous evidence suggests that substance P (SP) activates subpopulations of neurons within the dorsal motor nucleus of the vagus (DMV). In this study we aimed at identifying these subpopulations in r...

Neurokinin receptors modulate the impact of uncontrollable stimulation on adaptive spinal plasticity.

Behav. Neurosci. 121(5) , 1082-94, (2007)

Previous research has demonstrated that spinally transected rats can acquire a prolonged flexion response to prevent the delivery of shock. However, rats that receive shock irrespective of leg positio...

Intrathecal administration of neurokinin 1 and neurokinin 2 receptor antagonists undermines the savings effect in spinal rats seen in an instrumental learning paradigm.

Behav. Neurosci. 121(1) , 186-99, (2007)

Research has demonstrated that the isolated spinal cord is capable of modifying its behavior in response to changes in environmental stimuli. Previous studies have shown that rats with complete thorac...


More Articles

Related Compounds

  • neurokinin A (4-10), Tyr(5)-Trp(6,8,9)-Arg(10)-
  • [bAla8]-Neurokinin A(4-10)
  • (Nle10)-Neurokinin A (4-10)
  • (β-Ala8)-Neurokinin A (4-10)
  • [Lys5,MeLeu9,Nle10]Neurokinin A(4-10)
  • (Trp7,β-Ala8)-Neurokinin A (4-10)
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