10,11-methylenedioxycamptothecin

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Names

[ CAS No. ]:
135415-73-5

[ Name ]:
10,11-methylenedioxycamptothecin

[Synonym ]:
10H-1,3-Dioxolo(4,5-g)pyrano(3,4:6,7)indolizino(1,2-b)quinoline-8,11(7H,13H)-dione,7-ethyl-7-hydroxy-,(7S)
10,11-methylenedioxycamptothecin
10,11-methylenedioxy-20(S)-camptothecin
10,11-methlyenedioxycamptothecin

Chemical & Physical Properties

[ Density]:
1.64g/cm3

[ Boiling Point ]:
812.1ºC at 760mmHg

[ Molecular Formula ]:
C21H16N2O6

[ Molecular Weight ]:
392.36200

[ Flash Point ]:
445ºC

[ Exact Mass ]:
392.10100

[ PSA ]:
99.88000

[ LogP ]:
1.80830

Safety Information

[ Hazard Codes ]:
Xn

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (S)-4-ethyl-4-hydroxy-7,8-dihydro-1H-pyrano[3,4-f]indolizine-3,6,10(4H)-trione
  • 6-amino-1,3-benzodioxole-5-carbaldehyde
  • piperonal
  • (S)-4-ethyl-4-hydroxy-6-iodo-3-oxo-1H-pyrano[3,4-c]-8-pyridone
  • (S)-4-Ethyl-4-hydroxy-6-iodo-3-oxo-7-propargyl-1H-pyrano[3,4-c]-8-pyridone
  • 4-(trimethylsilyl)benzo[d][1,3]dioxole-5-carbaldehyde
  • (+/-)-4-ethyl-4-hydroxy-8-methoxy-6-(trimethylsilyl)-1,4-dihydro-3H-pyrano[3,4-c]pyridin-3-one

DownStream

Related Compounds

  • 10,11-Methylenedioxycamptothecin
  • 10,11-dihydrobenzo[a]anthracene
  • 10,11-Dihydrodiindeno(1,2-b:2',1'-d)thiophen-10,11-diol
  • 10,11-dimethoxy-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinolinylium
  • 10,11-dihydro-5-methyl-10-(methylammonio)-5H-dibenz[b,f]azepinium fumarate
  • 10,11-Dihydro-2,2,10,11-tetramethyl-8-phenyl-2H,6H,12H-benzo[1,2-b:3,4-b':5,6-b'']tripyran-6,12-dione