1H-Imidazole-1-ethanol,a-(fluoromethyl)-2-nitro-
Suppliers
Names
[ CAS No. ]:
13551-89-8
[ Name ]:
1H-Imidazole-1-ethanol,a-(fluoromethyl)-2-nitro-
[Synonym ]:
Fluoromisonidazole
1-(2-Hydroxy-3-fluoropropyl)-2-nitroimidazole
1-(2-Nitro-1-imidazolyl)-3-fluoro-2-propanol
Ro-07-0741
1-fluoro-3-(2-nitro-imidazol-1-yl)-propan-2-ol
SR 1367
SR 1369
KU 2210
1-(3-fluoro-2-hydroxypropyl)-2-nitroimidazole
Chemical & Physical Properties
[ Density]:
1.55 g/cm3
[ Boiling Point ]:
433.3ºC at 760 mmHg
[ Molecular Formula ]:
C6H8FN3O3
[ Molecular Weight ]:
189.14400
[ Flash Point ]:
215.8ºC
[ Exact Mass ]:
189.05500
[ PSA ]:
83.87000
[ LogP ]:
0.64490
[ Vapour Pressure ]:
2.82E-08mmHg at 25°C
[ Index of Refraction ]:
1.589
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NI5566000
- CHEMICAL NAME :
- Imidazole-1-ethanol, alpha-(fluoromethyl)-2-nitro-
- CAS REGISTRY NUMBER :
- 13551-89-8
- BEILSTEIN REFERENCE NO. :
- 0522249
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C6-H8-F-N3-O3
- MOLECULAR WEIGHT :
- 189.17
- WISWESSER LINE NOTATION :
- T5N CNJ A1YQ1F BNW
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 620 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Unreported
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 900 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Morphological transformation
- TEST SYSTEM :
- Rodent - mouse Embryo
- DOSE/DURATION :
- 1 mmol/L/3D (Continuous)
- REFERENCE :
- 45OJAG "Radiation Sensitizers: Their Use in the Clinical Management of Cancer, Proceedings of the Conference, Key Biscayne, FL, 1979," Brady, L.W., ed., New York, Masson Pub. USA, Inc., 1980 Volume(issue)/page/year: -,146,1980
Safety Information
[ HS Code ]:
2933290090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933290090
[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%