Avermectin B2a

Names

[ CAS No. ]:
135680-93-2

[ Name ]:
Avermectin B2a

Chemical & Physical Properties

[ Density]:
1.26g/cm3

[ Boiling Point ]:
966.4ºC at 760mmHg

[ Molecular Formula ]:
C48H74O15

[ Molecular Weight ]:
891.09200

[ Flash Point ]:
275.1ºC

[ Exact Mass ]:
890.50300

[ PSA ]:
190.29000

[ LogP ]:
4.57220

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.571

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CL1201300
CHEMICAL NAME :
Avermectin A(sub 1a), 22,23-dihydro-5-O-demethyl-23-hydroxy-, (13R,23S)-
CAS REGISTRY NUMBER :
135680-93-2
LAST UPDATED :
199406
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C48-H74-O15
MOLECULAR WEIGHT :
891.22

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
540 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 35,3873,1992

Related Compounds

  • Avermectin B2a
  • 5,4''-bis-O-(tert-butyldimethylsilyl)avermectin B2a
  • 5,4''-bis-O-(tert-butyldimethylsilyl)-23-O-(methanesulfonyl)avermectin B2a
  • Avermectin
  • Avermectin B1a monosaccharide
  • Avermectin A1a, 5-​O-​demethyl-​3,​4,​22,​23-​tetrahydro
  • (2R,3R,4R,5R)-5-((Benzoyloxy)methyl)-2-(2,4-dioxo-5-(trifluoromethyl)-3,4-dihydropyrimidin-1(2H)-yl)-3-methyltetrahydrofuran-3,4-diyl dibenzoate
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • 1,1-Dimethylethyl N-(5-cyclopentyl-2-methyl-5-oxopentyl)carbamate
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 1-[(5,6-Dichloropyridin-3-yl)methyl]cyclopropan-1-amine
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 5-Bromo-1H-pyrazolo[4,3-D]thiazole