2-Ethoxy-5-nitroaniline

Names

[ CAS No. ]:
136-79-8

[ Name ]:
2-Ethoxy-5-nitroaniline

[Synonym ]:
4-nitro-1-oxy-pyridine-2-carboxylic acid
4-nitro-p-phenetidine
4-nitropicolin acid-1-oxide
4-Nitro-2-amino-phenol-aethylaether
4-nitropicolinic acid 1-oxide
2-Aethoxy-5-nitro-anilin
4-Nitropyridine-2-carboxylic acid 1-oxide
5-Nitro-o-phenetidin
2-Amino-4-nitroethoxybenzen
4-nitro-picolinic acid N-oxide
2-ethoxy-5-nitro-aniline
4-Nitro-2-amino-phenetol
2-carboxy-4-nitropyridine-1-oxide
4-Nitro-1-oxy-pyridin-2-carbonsaeure

Chemical & Physical Properties

[ Density]:
1.264g/cm3

[ Boiling Point ]:
358.3ºC at 760 mmHg

[ Molecular Formula ]:
C8H10N2O3

[ Molecular Weight ]:
182.17700

[ Flash Point ]:
170.5ºC

[ Exact Mass ]:
182.06900

[ PSA ]:
81.07000

[ LogP ]:
2.68010

[ Vapour Pressure ]:
2.56E-05mmHg at 25°C

[ Index of Refraction ]:
1.585

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BX9740000
CHEMICAL NAME :
Aniline, 2-ethoxy-5-nitro-
CAS REGISTRY NUMBER :
136-79-8
BEILSTEIN REFERENCE NO. :
2720549
LAST UPDATED :
199709
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C8-H10-N2-O3

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
470 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AEPPAE Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. (Berlin, Ger.) V.110-253, 1925-66. For publisher information, see NSAPCC. Volume(issue)/page/year: 208,178,1949 ** OTHER MULTIPLE DOSE TOXICITY DATA **
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
2275 mg/kg/91D-I
TOXIC EFFECTS :
Liver - other changes Blood - other changes
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 1,326,1951

Safety Information

[ HS Code ]:
2922299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Benzene,1-ethoxy-2,4-dinitro-
  • o-Phenetidine
  • 2-ethoxy-5-nitro-benzamide
  • N-(2-ethoxyphenyl)-Acetamide
  • Ethanol
  • 1-Methoxy-2,4-dinitrobenzene

DownStream

Customs

[ HS Code ]: 2922299090

[ Summary ]:
2922299090. other amino-naphthols and other amino-phenols, other than those containing more than one kind of oxygen function, their ethers and esters; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Related Compounds

  • N-methyl-2-ethoxy-5-nitroaniline
  • 2-Ethoxy-5-(4-fluoro-benzoylamino)-benzenesulfonyl chloride
  • 2-ETHOXY-5-(TEREPHTHALAMIDO) BENZENE-1-SULFONYL CHLORIDE
  • 2-ethoxy-5-nitropyridine
  • 2-ethoxy-5-oxidophenazin-5-ium
  • 2-ETHOXY-5-TRIFLUOROMETHYLPHENYLBORONIC ACID
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • (S)-2-(2-(2-Aminoacetamido)acetamido)-3-(1H-imidazol-4-yl)propanoic acid 2,2,2-trifluoroacetate
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide