1-[(2R,4S)-4-azido-5-[(1R)-1,2-dihydroxyethyl]oxolan-2-yl]-5-methylpyrimidine-2,4-dione

Names

[ CAS No. ]:
136011-36-4

[ Name ]:
1-[(2R,4S)-4-azido-5-[(1R)-1,2-dihydroxyethyl]oxolan-2-yl]-5-methylpyrimidine-2,4-dione

[Synonym ]:
5'OHCH2alloAZT

Chemical & Physical Properties

[ Molecular Formula ]:
C11H15N5O5

[ Molecular Weight ]:
297.26700

[ Exact Mass ]:
297.10700

[ PSA ]:
154.56000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 1-(3-azido-2,3-dideoxy-5,6-O-isopropylidene-β-D-ribo-hexofuranosyl)thymine
  • 1,2-O-isopropylidene-3-O-methanesulfonyl-α-D-allofuranose
  • 2,3'-anhydro-1-(5',6'-di-O-benzoyl-β-D-glucofuranosyl)thymine
  • 1-(2'-O-acetyl-5',6'-di-O-benzoyl-3'-O-mesyl-β-D-allofuranosyl)thymine
  • Thymine

DownStream

  • Zidovudine