(2E)-2-(pyridin-2-ylmethylidene)-3,4-dihydronaphthalen-1-one

Names

[ CAS No. ]:
13640-50-1

[ Name ]:
(2E)-2-(pyridin-2-ylmethylidene)-3,4-dihydronaphthalen-1-one

[Synonym ]:
2-pyrilidene tetralone
HMS562P07
<pyridinylydene-2'>-2 tetralone

Chemical & Physical Properties

[ Density]:
1.214g/cm3

[ Boiling Point ]:
413ºC at 760 mmHg

[ Molecular Formula ]:
C16H13NO

[ Molecular Weight ]:
235.28100

[ Flash Point ]:
209.8ºC

[ Exact Mass ]:
235.10000

[ PSA ]:
29.96000

[ LogP ]:
3.29410

[ Vapour Pressure ]:
4.97E-07mmHg at 25°C

[ Index of Refraction ]:
1.664

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QK5054000
CHEMICAL NAME :
1(2H)-Naphthalenone, 3,4-dihydro-2-(2-pyridylmethylene)-
CAS REGISTRY NUMBER :
13640-50-1
BEILSTEIN REFERENCE NO. :
1461621
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H13-N-O
MOLECULAR WEIGHT :
235.30
WISWESSER LINE NOTATION :
L66 BVYT&J CU1- BT6NJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
147 mg/kg
TOXIC EFFECTS :
Behavioral - excitement
REFERENCE :
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 56,644,1967

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • 2-Pyridinecarboxaldehyde
  • 3,4-Dihydronaphthalen-1(2H)-one

DownStream

Related Compounds

  • N~3~-benzyl-6-isobutyl-N~3~-methyl-5,7-dioxo-4,5,6,7-tetrahydroisothiazolo[4,3-d]pyrimidine-3-carboxamide
  • 3-(1,4-dioxa-8-azaspiro[4.5]dec-8-ylcarbonyl)-6-isobutylisothiazolo[4,3-d]pyrimidine-5,7(4H,6H)-dione
  • 2-(2-(Trifluoromethyl)phenyl)thiazol-5-amine
  • 6-isobutyl-3-(4-(p-tolyl)piperazine-1-carbonyl)isothiazolo[4,3-d]pyrimidine-5,7(4H,6H)-dione
  • 6-benzyl-3-[(4-phenylpiperazino)carbonyl]isothiazolo[4,3-d]pyrimidine-5,7(4H,6H)-dione
  • 6-benzyl-3-{[4-(2-pyridyl)piperazino]carbonyl}isothiazolo[4,3-d]pyrimidine-5,7(4H,6H)-dione
  • Ensereptide
  • 3-[3,4-dihydro-2(1H)-isoquinolinylcarbonyl]-6-(4-fluorobenzyl)isothiazolo[4,3-d]pyrimidine-5,7(4H,6H)-dione
  • 1-(2-((2-Bromophenyl)amino)-2-oxoethyl)-6-oxo-2-phenyl-1,6-dihydropyrimidine-5-carboxamide
  • 3-(N-(4-ethoxyphenyl)-N-methylsulfamoyl)-N-(3-ethylphenyl)thiophene-2-carboxamide
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.