2-(3-Pyridylmethylene)-3,4-dihydro-1(2H)-naphthalenone

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Names

[ CAS No. ]:
13640-51-2

[ Name ]:
2-(3-Pyridylmethylene)-3,4-dihydro-1(2H)-naphthalenone

[Synonym ]:
(E)-4,5-Dihydro-4,4-dimethyl-2-(2-(3-nitrophenyl)ethenyl)oxazole monohydrochloride
(E)-2-(3-Nitrostyryl)-4,4-dimethyl-2-oxazoline hydrochloride
4,4-dimethyl-2-[(E)-2-(3-nitrophenyl)ethenyl]-5H-1,3-oxazole hydrochloride
Oxazole,4,5-dihydro-4,4-dimethyl-2-(2-(3-nitrophenyl)ethenyl)-,monohydrochloride,(E)
(E)-2-(3-Pyridyl)methylene-1-tetralone

Chemical & Physical Properties

[ Density]:
1.214g/cm3

[ Boiling Point ]:
415ºC at 760 mmHg

[ Molecular Formula ]:
C16H13NO

[ Molecular Weight ]:
235.28100

[ Flash Point ]:
210.9ºC

[ Exact Mass ]:
235.10000

[ PSA ]:
29.96000

[ LogP ]:
3.29410

[ Vapour Pressure ]:
4.27E-07mmHg at 25°C

[ Index of Refraction ]:
1.664

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QK5054010
CHEMICAL NAME :
1(2H)-Naphthalenone, 3,4-dihydro-2-(3-pyridylmethylene)-
CAS REGISTRY NUMBER :
13640-51-2
BEILSTEIN REFERENCE NO. :
1461622
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C16-H13-N-O
MOLECULAR WEIGHT :
235.30
WISWESSER LINE NOTATION :
L66 BVYT&J CU1- CT6NJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
147 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness
REFERENCE :
JPMSAE Journal of Pharmaceutical Sciences. (American Pharmaceutical Assoc., 2215 Constitution Ave., NW, Washington, DC 20037) V.50- 1961- Volume(issue)/page/year: 56,644,1967

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Nicotinaldehyde
  • 3,4-Dihydronaphthalen-1(2H)-one

DownStream

Related Compounds

  • N-(2-chloro-4-methylphenyl)-6-(piperidin-1-yl)pyridazine-3-carboxamide
  • N-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-6-(piperidin-1-yl)pyridazine-3-carboxamide
  • 2-(3-chlorophenyl)-1-[(2S)-pyrrolidine-2-carbonyl]pyrrolidine hydrochloride
  • 6-(piperidin-1-yl)-N-(4-(trifluoromethoxy)benzyl)pyridazine-3-carboxamide
  • N-(4-(3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)phenyl)-6-(piperidin-1-yl)pyridazine-3-carboxamide
  • N-(2-chloro-5-(trifluoromethyl)phenyl)-6-morpholinopyridazine-3-carboxamide
  • 2-(3,5-Dichlorophenyl)-2-(methylamino)acetic acid hydrochloride
  • N-(4-butylphenyl)-6-morpholinopyridazine-3-carboxamide
  • N-(3-fluoro-4-methylphenyl)-6-morpholinopyridazine-3-carboxamide
  • N-(2-methoxy-5-methylphenyl)-6-morpholinopyridazine-3-carboxamide
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