Abacavir

Suppliers

Names

[ CAS No. ]:
136470-78-5

[ Name ]:
Abacavir

[Synonym ]:
MFCD00903850
(1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol
(1S,cis)-4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol
2-Cyclopentene-1-methanol, 4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-, (1S,4R)-
Abacavir
2-Cyclopentene-1-methanol, 4-[2-amino-6-(cyclopropylamino)-9H-purin-9-yl]-, (1S,4R)-
2-Cyclopentene-1-methanol, 4-(2-amino-6-(cyclopropylamino)-9H-purin-9-yl)-, (1S-cis)-
{(1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopenten-1-yl}methanol
{(1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol
{(4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
636.0±65.0 °C at 760 mmHg

[ Melting Point ]:
161 °C(dec.)

[ Molecular Formula ]:
C14H18N6O

[ Molecular Weight ]:
286.332

[ Flash Point ]:
338.4±34.3 °C

[ Exact Mass ]:
286.154205

[ PSA ]:
101.88000

[ LogP ]:
0.72

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.864

[ Storage condition ]:
0-6°C

MSDS

Click to get detail MSDS

Safety Information

[ Hazard Codes ]:
T,N

[ Risk Phrases ]:
R21:Harmful in contact with skin. R23/25:Toxic by inhalation and if swallowed . R43:May cause sensitization by skin contact. R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment .

[ Safety Phrases ]:
S36/37-S45-S60-S61

[ RIDADR ]:
UN 2810

[ RTECS ]:
TE3850000

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (-)-N-{6-(cyclopropylamino)-9-[(1R,4S)-4-(hydroxymethyl)cyclopent-2-enyl]-9H-purin-2-yl}isobutyramide
  • 2-Amino-6-chloropurine
  • Cyclopropanamine
  • cis-3-benzoyloxy-4-(hydroxymethyl)cyclopentene
  • ((1S,4R)-4-(2-chloro-6-(cyclopropylamino)-9H-purin-9-yl)cyclopent-2-en-1-yl)methanol
  • [4S,2R,3R]-(4-benzyl-2-thioxooxazolidin-3-yl)(2-hydroxycyclopent-3-enyl)methanone

DownStream

Related Compounds

  • abacavir
  • Abacavir
  • (3-Aminopiperidin-1-yl)(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)methanone hydrochloride
  • (3-Aminopiperidin-1-yl)(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)methanone hydrochloride
  • (3-Aminopiperidin-1-yl)(benzo[d][1,3]dioxol-5-yl)methanone hydrochloride
  • 1-(3-Aminopiperidin-1-yl)-2-(thiophen-3-yl)ethanone hydrochloride
  • 1-(5-Chloropyrimidin-2-yl)piperidin-3-amine hydrochloride
  • 1-(5-Fluoropyrimidin-2-yl)piperidin-3-amine hydrochloride
  • 1-(4-Chloropyrimidin-2-yl)piperidin-3-amine hydrochloride
  • 2-(3-Aminopiperidin-1-yl)pyridin-3-ol hydrochloride
  • 1-(5-nitro-1H-benzo[d]imidazol-2-yl)piperidin-3-amine hydrochloride
  • 3-(3-aminopiperidin-1-yl)-N-cyclopropylquinoxalin-2-amine hydrochloride
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