Alprenolol
Suppliers
Names
Chemical & Physical Properties
[ Density]:
1.007g/cm3
[ Boiling Point ]:
383.4ºC at 760mmHg
[ Melting Point ]:
57.5°C
[ Molecular Formula ]:
C15H23NO2
[ Molecular Weight ]:
249.34900
[ Flash Point ]:
185.7ºC
[ Exact Mass ]:
249.17300
[ PSA ]:
41.49000
[ LogP ]:
2.54370
[ Vapour Pressure ]:
1.46E-06mmHg at 25°C
[ Index of Refraction ]:
1.5250 (estimate)
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UA5350000
- CHEMICAL NAME :
- 2-Propanol, 1-(o-allylphenoxy)-3-(isopropylamino)-
- CAS REGISTRY NUMBER :
- 13655-52-2
- LAST UPDATED :
- 199606
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C15-H23-N-O2
- MOLECULAR WEIGHT :
- 249.39
- WISWESSER LINE NOTATION :
- 1Y1&M1YQ1OR B2U1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Human - woman
- DOSE/DURATION :
- 210 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- UGLAAD Ugeskrift for Laeger. Doctor's Weekly. (Almindelige Danske Laegeforening, Esplanaden 8C4, 1045 Copenhagen K, Denmark) V.1- 1839- Volume(issue)/page/year: 139,2817,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 90 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- EJMCA5 European Journal of Medicinal Chemistry--Chimie Therapeutique. (Editions Scientifiques Elsevier, 29 rue Buffon, F-75005, Paris, France) V.9- 1974- Volume(issue)/page/year: 18,151,1983
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 20 mg/kg
- TOXIC EFFECTS :
- Autonomic Nervous System - sympathomimetic
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 27,1022,1977
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 184 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 8,137,1974
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 102 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- PCJOAU Pharmaceutical Chemistry Journal (English Translation). Translation of KHFZAN. (Plenum Pub. Corp., 233 Spring St., New York, NY 10013) No.1- 1967- Volume(issue)/page/year: 8,137,1974
Safety Information
[ Hazard Codes ]:
T: Toxic;
[ Risk Phrases ]:
R23/24/25
[ Safety Phrases ]:
36/37/39-45
[ RIDADR ]:
UN 3249
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1(b)