BQ-123

Names

[ Name ]:
BQ-123

[Synonym ]:
Cyclo(L-α-aspartyl-L-prolyl-D-valyl-L-leucyl-D-tryptophyl)
d-trp-d-asp-pro-d-val-leu
bq-518
MFCD00133204
BQ-123
m.w. 610.70 c31h42n6o7

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
1053.6±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₁H₄₂N₆O₇

[ Molecular Weight ]:
610.701

[ Flash Point ]:
591.0±34.3 °C

[ Exact Mass ]:
610.311523

[ PSA ]:
189.80000

[ LogP ]:
-0.10

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.621

[ Storage condition ]:
-20℃

MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

Boc-Leu-OH.H2O
Boc-D-Valine
Boc-D-Trp-OH
boc-d-asp-ofm

DownStream

Articles

A dual role for NOTCH signaling in joint cartilage maintenance and osteoarthritis.

Sci. Signal. 8 , ra71, (2015)

Loss of NOTCH signaling in postnatal murine joints results in osteoarthritis, indicating a requirement for NOTCH during maintenance of joint cartilage. However, NOTCH signaling components are substant...

Subnormothermic ex vivo liver perfusion reduces endothelial cell and bile duct injury after donation after cardiac death pig liver transplantation.

Liver Transpl. 20(11) , 1296-305, (2014)

An ischemic-type biliary stricture (ITBS) is a common feature after liver transplantation using donation after cardiac death (DCD) grafts. We compared sequential subnormothermic ex vivo liver perfusio...

Gene expression profiling and endothelin in acute experimental pancreatitis.

World J. Gastroenterol. 18(32) , 4257-69, (2012)

To analyze gene expression profiles in an experimental pancreatitis and provide functional reversal of hypersensitivity with candidate gene endothelin-1 antagonists.Dibutyltin dichloride (DBTC) is a c...

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