NS-102

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Names

[ CAS No. ]:
136623-01-3

[ Name ]:
NS-102

[Synonym ]:
1H-Benz[g]indole-2,3-dione,6,7,8,9-tetrahydro-5-nitro-,3-oxime
NS 102
6,7,8,9-Tetrahydro-5-nitro-1H-benz[g]indole-2,3-dione 3-oxime

Chemical & Physical Properties

[ Density]:
1.74g/cm3

[ Boiling Point ]:
405.8ºC at 760mmHg

[ Molecular Formula ]:
C12H11N3O4

[ Molecular Weight ]:
261.23300

[ Flash Point ]:
199.2ºC

[ Exact Mass ]:
261.07500

[ PSA ]:
107.51000

[ LogP ]:
2.13230

[ Vapour Pressure ]:
2.81E-08mmHg at 25°C

[ Index of Refraction ]:
1.794

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Selective block of recombinant glur6 receptors by NS-102, a novel non-NMDA receptor antagonist.

Eur. J. Pharmacol. 269 , 43, (1994)

The diversity of neuronal glutamate receptors continues to increase with the discovery of multiple subunits and subunit families. The significance of this potential receptor heterogeneity is unknown b...

A novel non-NMDA receptor antagonist shows selective displacement of low-affinity [3H]kainate binding.

Eur. J. Pharmacol. 246 , 195, (1993)

5-Nitro-6,7,8,9-tetrahydrobenzo[G]indole-2,3-dione-3-oxime (NS-102), a new competitive glutamate receptor antagonist displaced binding to non-N-methyl-D-aspartate (non-NMDA) binding sites with no acti...

Kainate receptor-mediated inhibition of presynaptic Ca2+ influx and EPSP in area CA1 of the rat hippocampus.

J. Physiol. 509 ( Pt 3) , 833-45, (1998)

1. The effect of a low concentration (1 microM) of kainate (kainic acid; KA) on presynaptic calcium (Ca2+) influx at the Schaffer collateral-commissural (SCC) synapse was examined in rat hippocampal s...


More Articles


Related Compounds

  • NS-398
  • NS-8
  • NS-062
  • NS-187(HCL SALT)
  • NS-018
  • NS-1643
  • 2-(1-isobutyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)ethan-1-amine
  • N-(2-(3-(thiophen-2-yl)-1H-pyrazol-1-yl)ethyl)benzofuran-2-carboxamide
  • 3-((4-(thiophen-2-yl)-1H-pyrazol-1-yl)methyl)piperidine
  • (E)-1-((1R,5S)-3-(phenylsulfonyl)-8-azabicyclo[3.2.1]octan-8-yl)-3-(thiophen-2-yl)prop-2-en-1-one
  • Methyl 2-((1-(2,2-diphenylacetyl)piperidin-4-yl)sulfonyl)acetate
  • methyl 2-((1-(2-(6-oxopyridazin-1(6H)-yl)acetyl)piperidin-4-yl)sulfonyl)acetate
  • 4-methoxy-1-phenyl-5-(4-(phenylsulfonyl)piperidine-1-carbonyl)pyridin-2(1H)-one
  • N-(4-(3-methoxypiperidin-1-yl)phenyl)benzo[c][1,2,5]thiadiazole-5-carboxamide
  • 6-Bromo-2-methoxypyrazolo[1,5-a]pyrimidine
  • (5-(Hydroxymethyl)thiazol-2-yl)(phenyl)methanone
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