1-(2,6-Difluorophenyl)ethanone

Suppliers

Names

[ CAS No. ]:
13670-99-0

[ Name ]:
1-(2,6-Difluorophenyl)ethanone

[Synonym ]:
2,6-Difluoroacetophenone
2′,6′-Difluoroacetophenone
EINECS 237-151-9
2’,6’-Difluoroacetophenone
2',6'-Difluoroacetophenone
MFCD00000328
1-(2,6-Difluorophenyl)ethanone
2-Acetyl-1,3-difluorobenzene
Ethanone, 1-(2,6-difluorophenyl)-
2‘,6‘-Difluoroacetophenone
1-(2,6-Difluorophenyl)ethan-1-one

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
178.6±20.0 °C at 760 mmHg

[ Molecular Formula ]:
C8H6F2O

[ Molecular Weight ]:
156.129

[ Flash Point ]:
76.7±0.0 °C

[ Exact Mass ]:
156.038666

[ PSA ]:
17.07000

[ LogP ]:
0.96

[ Vapour Pressure ]:
1.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.473

MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Precursor & DownStream

Precursor

  • 2,6-Difluorobenzoyl chloride
  • Diethyl malonate
  • Potassium monoethyl malonate
  • 2,6-Difluorobenzonitrile
  • Acetyl chloride
  • 1,3-difluoro-2-trimethylsilylbenzene
  • METHYLLITHIUM
  • 1,3-Difluorobenzene
  • Ethanoic anhydride
  • (2,6-difluorophenyl)lithium

DownStream

  • 1-(2,6-Difluorophenyl)ethanol
  • 2-Bromo-1-(2,6-difluorophenyl)ethanone
  • 4-FLUORO-3-METHYL-1H-INDAZOLE
  • 3-(2,6-Difluorophenyl)-3-oxopropanenitrile

Articles

Synthesis of 2-aminoquinazolines from ortho-fluoroketones. Hynes JB, et al.

J. Heterocycl. Chem. 32(4) , 1185-87, (1995)

Ruthenium-catalyzed arylation of fluorinated aromatic ketones via< i> ortho</i>-selective carbon-fluorine bond cleavage. Kawamoto K, et al.

Tetrahedron Lett. 52(44) , 5888-5890, (2011)


More Articles


Related Compounds

  • 2-Bromo-1-(2,6-difluorophenyl)ethanone
  • 2-Chloro-1-(2,6-difluorophenyl)ethanone
  • (Z)-1-(2,6-DIFLUOROPHENYL)ETHANONE OXIME
  • 1-[(2,6-difluorophenyl)methyl]-2-phenylbenzimidazole
  • 1-[(2,6-difluorophenyl)methyl]-3-(4-ethyl-1,3-thiazol-2-yl)thiourea
  • 1-(2,6-difluorophenyl)-3H-indol-2-one
  • 2-[2-(Benzyloxy)phenyl]cyclobutan-1-one
  • N-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]oxy}ethyl)-3-(trifluoromethyl)benzamide
  • N-(2-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}ethyl)benzenecarboxamide
  • L-Prolyl-L-alanyl-N~5~-(diaminomethylidene)-L-ornithyl-L-prolyl-L-threonyl-L-seryl-L-prolyl-L-proline
  • N-[2-Hydroxy-3-(tetradecyloxy)propyl]tyrosine
  • Ketone, 10b-fluoro-1,2,3,3a,3b,4,5,8,10,10a,10b,11,12,12a-tetradecahydro-1,11-dihydroxy-2,10a,12a-trimethylcyclopenta[7,8]phenanthro[2,3-c]pyrazol-1-yl hydroxymethyl
  • 2-(Cyclopropylmethoxy-d4)-acetic Acid
  • [2-[2-[2-[[6-amino-2-[3-amino-1-[(2,3-diamino-3-oxopropyl)amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[5-[[1-[2-[4-[4-[4-[carbamimidoyl-[4-(diaminomethylideneamino)butyl]amino]butylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]ethylamino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-4-methyl-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate;hydrochloride
  • 5,14-Dihydroxy-3-[(2-methylpropanoyl)oxy]-19-oxocard-20(22)-enolide
  • N-(2-{[3-chloro-5-(trifluoromethyl)-2-pyridinyl]oxy}ethyl)-2,6-difluorobenzenecarboxamide
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.