1-[4-(3-chlorophenyl)piperazin-1-yl]-3-[(4-methyl-1,3-thiazol-5-yl)oxy]propan-2-ol,hydrochloride

Names

[ Name ]:
1-[4-(3-chlorophenyl)piperazin-1-yl]-3-[(4-methyl-1,3-thiazol-5-yl)oxy]propan-2-ol,hydrochloride

[Synonym ]:
B 1548
3-(4-m-Chlorophenylpiperazin-1-yl)-1-(4-methylthiazolyl-5-oxy)propan-2-ol hydrochloride
1-[4-(3-chlorophenyl)piperazin-1-yl]-3-[(4-methyl-1,3-thiazol-5-yl)oxy]propan-2-ol hydrochloride

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₇H₂₃Cl₂N₃O₂S

[ Molecular Weight ]:
404.35400

[ Exact Mass ]:
403.08900

[ PSA ]:
77.07000

[ LogP ]:
3.47170

[ Vapour Pressure ]:
2.02E-13mmHg at 25°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TL7775010

CHEMICAL NAME :: 1-Piperazineethanol, 4-(3-chlorophenyl)-alpha-(((4-methyl-5-thiazolyl)oxy) methyl)-, monohydrochloride

CAS REGISTRY NUMBER :: 136996-83-3

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C17-H22-Cl-N3-O2-S.Cl-H

MOLECULAR WEIGHT :: 404.39

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: USXXAM United States Patent Document. (U.S. Patent Office, Box 9, Washington, DC 20231) Volume(issue)/page/year: #5322846

Related Compounds

3-chloro-5-ethynyl-N,N-dimethylpyrazin-2-amine
5-(6-Chloro-5-methylpyridin-3-yl)-1,2-oxazole-4-carboxylic acid
2-chloro-3-methyl-5-[(2S)-oxiran-2-yl]pyridine
methyl 5-(3-chloroprop-1-en-2-yl)-1-methyl-1H-pyrazole-4-carboxylate
3-{5-Chlorothieno[3,2-b]pyridin-2-yl}butan-1-amine
N-({5-chlorothieno[3,2-b]pyridin-2-yl}methyl)-N-methylhydroxylamine
2-(6-chloro-1-methyl-1H-indol-3-yl)-2-fluoroethan-1-amine
6-chloro-1-methyl-3-(prop-2-yn-1-yl)-1H-indole
1-(4-Bromo-3-chlorophenyl)-2,2-dichloroethanol
2-(6-chloro-1-methyl-1H-indol-3-yl)prop-2-en-1-amine