2-Methylbutan-1-ol

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Names

[ CAS No. ]:
137-32-6

[ Name ]:
2-Methylbutan-1-ol

[Synonym ]:
(±)-2-Methyl-1-butanol
butan-1-ol, 2-methyl-
DL-sec-Butylcarbinol (Synthetic)
1-Butanol, 2-methyl-
DL-2-Methyl-1-butanol
EINECS 205-289-9
2-methyl-n-butanol
2-Methylbutyl alcohol
2-methylbutanol
2-Methyl-1-butanol,natural
2-Methyl-1-butanol
1-Butanol, 2-methyl-, (±)-
methyl-2-butan-1-ol
MFCD00004743

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
128.7±0.0 °C at 760 mmHg

[ Melting Point ]:
-70ºC

[ Molecular Formula ]:
C5H12O

[ Molecular Weight ]:
88.148

[ Flash Point ]:
43.3±0.0 °C

[ Exact Mass ]:
88.088814

[ PSA ]:
20.23000

[ LogP ]:
1.22

[ Vapour density ]:
3 (vs air)

[ Vapour Pressure ]:
4.8±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.405

[ Water Solubility ]:
3.6 g/100 mL (30 ºC)

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
EL5250000
CHEMICAL NAME :
1-Butanol, 2-methyl-
CAS REGISTRY NUMBER :
137-32-6
BEILSTEIN REFERENCE NO. :
1718810
LAST UPDATED :
199710
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
C5-H12-O
MOLECULAR WEIGHT :
88.17
WISWESSER LINE NOTATION :
Q1Y2&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Open irritation test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Behavioral - ataxia
REFERENCE :
SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 116,663,1952
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1900 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 27,1,1945
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
3540 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Parenteral
SPECIES OBSERVED :
Amphibian - frog
DOSE/DURATION :
2448 mg/kg
TOXIC EFFECTS :
Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - somnolence (general depressed activity)
REFERENCE :
AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 50,296,1935

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H315-H319-H332-H335

[ Precautionary Statements ]:
P210-P261-P280-P304 + P340 + P312-P337 + P313-P403 + P235

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R10;R20;R37;R66

[ Safety Phrases ]:
S46

[ RIDADR ]:
UN 1105

[ WGK Germany ]:
3

[ RTECS ]:
EL5250000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
29051500

Synthetic Route

Precursor & DownStream

Precursor

  • 2-Methylbut-2-ene
  • 1-Penten-3-one
  • (3S)-oxolan-3-ylmethanol
  • Ethyl isovalerate
  • 1,4-Dioxane
  • 2-Ethacrolein
  • diethyl isopropylmalonate
  • Diethyl ethylmalonate
  • 1-Propanol
  • Ethanol

DownStream

  • 2,6,10-Trimethyldodecane
  • 1-Bromo-2-methylbutane
  • 3-Pyridinecarboxamide,4-methyl-
  • 1-Iodo-2-methylbutane (stabilized with Copper chip)
  • (S)-1-Bromo-2-methylbutane
  • (2R)-1-Bromo-2-methylbutane
  • 3-Methylbutanoic acid
  • Formic Acid
  • 2-Butanone
  • Chloroform

Customs

[ HS Code ]: 2905199090

[ Summary ]:
2905199090. saturated monohydric alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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Related Compounds

  • (R)-2-methylbutan-1-ol
  • (S)-2-methylbutan-1-ol
  • 2-amino-2-methylbutan-1-ol
  • 4-amino-2-methylbutan-1-ol
  • 2-ethyl-2-methylbutan-1-ol
  • 4-chloro-2-methylbutan-1-ol
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 4-Methyl-3-(pentan-2-yl)cyclohexan-1-one
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 4-[(3-Fluoro-4-methylphenyl)amino]pyrimidine-2-carbonitrile
  • Sodium 3-acetamido-4-hydroxybenzene-1-sulfinate
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde