2-Methylbutan-1-ol

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Names

[ CAS No. ]:
137-32-6

[ Name ]:
2-Methylbutan-1-ol

[Synonym ]:
(±)-2-Methyl-1-butanol
butan-1-ol, 2-methyl-
DL-sec-Butylcarbinol (Synthetic)
1-Butanol, 2-methyl-
DL-2-Methyl-1-butanol
EINECS 205-289-9
2-methyl-n-butanol
2-Methylbutyl alcohol
2-methylbutanol
2-Methyl-1-butanol,natural
2-Methyl-1-butanol
1-Butanol, 2-methyl-, (±)-
methyl-2-butan-1-ol
MFCD00004743

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
128.7±0.0 °C at 760 mmHg

[ Melting Point ]:
-70ºC

[ Molecular Formula ]:
C₅H₁₂O

[ Molecular Weight ]:
88.148

[ Flash Point ]:
43.3±0.0 °C

[ Exact Mass ]:
88.088814

[ PSA ]:
20.23000

[ LogP ]:
1.22

[ Vapour density ]:
3 (vs air)

[ Vapour Pressure ]:
4.8±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.405

[ Water Solubility ]:
3.6 g/100 mL (30 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: EL5250000

CHEMICAL NAME :: 1-Butanol, 2-methyl-

CAS REGISTRY NUMBER :: 137-32-6

BEILSTEIN REFERENCE NO. :: 1718810

LAST UPDATED :: 199710

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C5-H12-O

MOLECULAR WEIGHT :: 88.17

WISWESSER LINE NOTATION :: Q1Y2&1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Open irritation test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1 gm/kg

TOXIC EFFECTS :: Behavioral - ataxia

REFERENCE :: SCIEAS Science. (American Assoc. for the Advancement of Science, 1333 H St., NW, Washington, DC 20005) V.1- 1895- Volume(issue)/page/year: 116,663,1952

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1900 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JIHTAB Journal of Industrial Hygiene and Toxicology. (Cambridge, MA) V.18-31, 1936-49. For publisher information, see AEHLAU. Volume(issue)/page/year: 27,1,1945

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 3540 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 23,95,1962

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Parenteral

SPECIES OBSERVED :: Amphibian - frog

DOSE/DURATION :: 2448 mg/kg

TOXIC EFFECTS :: Peripheral Nerve and Sensation - spastic paralysis with or without sensory change Behavioral - somnolence (general depressed activity)

REFERENCE :: AIPTAK Archives Internationales de Pharmacodynamie et de Therapie. (Heymans Institute of Pharmacology, De Pintelaan 185, B-9000 Ghent, Belgium) V.4- 1898- Volume(issue)/page/year: 50,296,1935

Safety Information

[ Symbol ]:

GHS02, GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H226-H315-H319-H332-H335

[ Precautionary Statements ]:
P210-P261-P280-P304 + P340 + P312-P337 + P313-P403 + P235

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R10;R20;R37;R66

[ Safety Phrases ]:
S46

[ RIDADR ]:
UN 1105

[ WGK Germany ]:
3

[ RTECS ]:
EL5250000

[ Packaging Group ]:
III

[ Hazard Class ]:
3

[ HS Code ]:
29051500

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

2-Methylbut-2-ene
1-Penten-3-one
(3S)-oxolan-3-ylmethanol
Ethyl isovalerate
1,4-Dioxane
2-Ethacrolein
diethyl isopropylmalonate
Diethyl ethylmalonate
1-Propanol
Ethanol

DownStream

2,6,10-Trimethyldodecane
1-Bromo-2-methylbutane
3-Pyridinecarboxamide,4-methyl-
1-Iodo-2-methylbutane (stabilized with Copper chip)
(S)-1-Bromo-2-methylbutane
(2R)-1-Bromo-2-methylbutane
3-Methylbutanoic acid
Formic Acid
2-Butanone
Chloroform

Customs

[ HS Code ]: 2905199090

[ Summary ]:
2905199090. saturated monohydric alcohols. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%

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