(S)-Crizotinib

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Names

[ CAS No. ]:
1374356-45-2

[ Name ]:
(S)-Crizotinib

[Synonym ]:
(S)-Crizotinib
(S)-crizotinib

Chemical & Physical Properties

[ Molecular Formula ]:
C21H22Cl2FN5O

[ Molecular Weight ]:
450.33700

[ Exact Mass ]:
449.11900

[ PSA ]:
77.99000

[ LogP ]:
5.94770

[ Storage condition ]:
-20℃

MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1.

Onco. Targets Ther. 8 , 3649-64, (2015)

Inhibition of the nucleotide pool sanitizing enzyme MTH1 causes extensive oxidative DNA damages and apoptosis in cancer cells and hence may be used as an anticancer strategy. As natural products have ...


More Articles


Related Compounds

  • (S)-3-(BENZYLOXY)-2-(((TERT-BUTOXYCARBONYL)AMINO)METHYL)PROPANOIC ACID
  • (S)-1-(Naphthalen-1-yl)propan-1-amine hydrochloride
  • (S)-1-(p-tolyl)ethyl 2,3,4,5,6-pentafluorobenzoate
  • (S)-1-(4-bromophenylsulfonyl)pyrrolidin-3-ol
  • S-[4-[2-(4-formamidophenyl)ethynyl]phenyl] ethanethioate
  • (S)-2,4-dimethyl-docos-2t-enoic acid methyl ester
  • tert-butyl N-[3-chloro-4-(chloromethyl)phenyl]carbamate
  • tert-butyl N-[4-(aminomethyl)-3-hydroxyphenyl]carbamate
  • tert-butyl N-[4-(aminomethyl)-3-methoxyphenyl]carbamate
  • tert-butyl N-[3-hydroxy-4-(hydroxymethyl)phenyl]carbamate
  • tert-butyl N-[4-(hydroxymethyl)-3-methoxyphenyl]carbamate
  • tert-butyl N-[4-(chloromethyl)-2-methylphenyl]carbamate
  • tert-butyl N-[4-(aminomethyl)-2-chlorophenyl]carbamate
  • tert-butyl N-[2-fluoro-4-(hydroxymethyl)phenyl]carbamate
  • tert-butyl N-[2-chloro-4-(hydroxymethyl)phenyl]carbamate
  • N-(4-Fluoro-3-methoxyphenyl)methanesulfonamide
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