tert-Butyl (2R)-2-methylpyrrolidine-1-carboxylate

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Names

[ CAS No. ]:
137496-71-0

[ Name ]:
tert-Butyl (2R)-2-methylpyrrolidine-1-carboxylate

[Synonym ]:
2-Methyl-2-propanyl (2R)-2-methyl-1-pyrrolidinecarboxylate
2-methylpyrrolidine-1-carboxylic acid tert-butyl ester
tert-Butyl (2R)-2-methylpyrrolidine-1-carboxylate
2-Methyl-2-propanyl (2S)-2-methyl-1-pyrrolidinecarboxylate
1-Pyrrolidinecarboxylic acid, 2-methyl-, 1,1-dimethylethyl ester, (2R)-
1-Pyrrolidinecarboxylic acid, 2-methyl-, 1,1-dimethylethyl ester, (2S)-

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
234.0±9.0 °C at 760 mmHg

[ Molecular Formula ]:
C10H19NO2

[ Molecular Weight ]:
185.263

[ Flash Point ]:
95.3±18.7 °C

[ Exact Mass ]:
185.141586

[ PSA ]:
29.54000

[ LogP ]:
1.99

[ Vapour Pressure ]:
0.1±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.463

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05, GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H315-H318-H335-H400

[ Precautionary Statements ]:
P261-P273-P280-P301 + P310-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
T: Toxic;N: Dangerous for the environment;

[ Risk Phrases ]:
R25;R37/38;R41;R50

[ Safety Phrases ]:
S26-S39-S45-S61

[ RIDADR ]:
UN 2810

[ HS Code ]:
2933990090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (R)-1-[(1,1-dimethylethoxy)carbonyl]-2-pyrrolidinemethanolmethanesulfonate
  • (R)-TERT-BUTYL 2-((TOSYLOXY)METHYL)PYRROLIDINE-1-CARBOXYLATE
  • 2-Methyl-2-propanyl 1-pyrrolidinecarboxylate
  • Dimethyl sulfate
  • Di-tert-butyl dicarbonate
  • 2-Methylpyrrolidine
  • tert-butyl (2R)-2-(hydroxymethyl)-1-pyrrolidinecarboxylate
  • Boc-D-Pro-OH
  • methyl iodide

DownStream

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • tert-Butyl (2R)-2-methylpyrrolidine-1-carboxylate
  • tert-butyl (2R,4R)-4-{[tert-butyl(dimethyl)silyl]oxy}-2-methylpyrrolidine-1-carboxylate
  • (2R,4R)-(+)-AZETIDINE-2,4-DICARBOXYLICACID
  • tert-butyl 2-Methylpyrrolidine-1-carboxylate
  • tert-butyl (2R)-2-allylpiperidine-1-carboxylate
  • tert-butyl (2R)-2-butylpiperazine-1-carboxylate,hydrochloride
  • tert-butyl N-{2-hydroxy-3-methoxy-5-[(pyrrolidin-3-yl)methyl]phenyl}carbamate
  • tert-butyl N-{2-hydroxy-5-[(3R)-3-hydroxybutyl]-3-methoxyphenyl}carbamate
  • tert-butyl N-[2-hydroxy-3-methoxy-5-(nitromethyl)phenyl]carbamate
  • tert-butyl N-[5-(azetidin-3-yl)-2-hydroxy-3-methoxyphenyl]carbamate
  • tert-butyl N-[2-hydroxy-3-methoxy-5-(2-nitroethyl)phenyl]carbamate
  • tert-butyl 3-(2,3-dihydro-1H-inden-4-yl)piperazine-1-carboxylate
  • tert-butyl N-[2-amino-1-(2-tert-butyl-2H-1,2,3,4-tetrazol-5-yl)ethyl]carbamate
  • rac-tert-butyl N-{4-[(1R,3R)-3-amino-2,2-dimethylcyclopropyl]-3-methoxyphenyl}carbamate
  • tert-butyl N-{4-[2-(1-hydroxycyclopropyl)ethyl]-3-methoxyphenyl}carbamate
  • tert-butyl N-[4-(1-acetylcyclopropyl)-3-methoxyphenyl]carbamate
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