4-[(morpholinothio)thioxomethyl]morpholine

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Names

[ CAS No. ]:
13752-51-7

[ Name ]:
4-[(morpholinothio)thioxomethyl]morpholine

[Synonym ]:
N-oxydiethylene thiocarbamyl-N-oxydiethylene sulfenamide
Morpholine,4-[(4-morpholinylthio)thioxomethyl]
4-((Morpholinothiocarbonyl)thio)morpholine
N,N'-Di-(oxidiethylen)-thiocarbamylsulfenamid
4-[(morpholinothio)thioxomethyl]morpholine
Accelerator otos
OTOS
EINECS 237-335-9
Morpholino-thiocarbamoyl-sulfensaeuremorpholid
Cure-Rite 18
4-(morpholine-4-carbothioylsulfanyl)-morpholine

Chemical & Physical Properties

[ Density]:
1.34g/cm3

[ Boiling Point ]:
378.1ºC at 760mmHg

[ Melting Point ]:
139 °C

[ Molecular Formula ]:
C9H16N2O2S2

[ Molecular Weight ]:
248.36600

[ Exact Mass ]:
248.06500

[ PSA ]:
82.33000

[ LogP ]:
0.45970

[ Vapour Pressure ]:
6.45E-06mmHg at 25°C

[ Index of Refraction ]:
1.631

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
QE7189000
CHEMICAL NAME :
Morpholine, 4-((morpholinothiocarbonyl)thio)-
CAS REGISTRY NUMBER :
13752-51-7
LAST UPDATED :
199710
DATA ITEMS CITED :
9
MOLECULAR FORMULA :
C9-H16-N2-O2-S2
MOLECULAR WEIGHT :
248.39
WISWESSER LINE NOTATION :
T6N DSTJ AVS- AT6N DOTJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
28476 mg/kg/2.2Y-C
TOXIC EFFECTS :
Kidney, Ureter, Bladder - changes in tubules (including acute renal failure, acute tubular necrosis) Kidney, Ureter, Bladder - other changes Nutritional and Gross Metabolic - weight loss or decreased weight gain
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Oral
DOSE :
302 mg/kg
SEX/DURATION :
male 12 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Effects on Newborn - weaning or lactation index (e.g., # alive at weaning per # alive at day 4)

MUTATION DATA

TYPE OF TEST :
Cytogenetic analysis
TEST SYSTEM :
Rodent - hamster Ovary
DOSE/DURATION :
2500 ug/L
REFERENCE :
ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 5,193,1983

Safety Information

[ HS Code ]:
2934999090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • morpholine
  • acetyl-trichloromethyl-disulfane

DownStream

Customs

[ HS Code ]: 2934999090

[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • 4-[[4-(dimethylamino)phenyl]thioxomethyl]-Morpholine
  • 4-[(2,4-dichlorophenyl)thioxomethyl]morpholine
  • 4-(morpholine-4-carbonyl)benzonitrile
  • 4-(morpholine-4-carbonyl)-9H-fluoren-9-one
  • 4-(Morpholine-4-carbonyl)phenylboronic Acid Pinacol Ester
  • 4-(morpholine-4-carbonyl)benzonitrile
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 3-[(2-Methylpropan-2-yl)oxycarbonylamino]-5,6,7,8-tetrahydronaphthalene-2-carboxylic acid
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde
  • tert-Butyl-DL-alanine
  • 4-amino-N-[2-tert-butyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-1H-benzimidazol-5-yl]-N-ethylbenzenesulfonamide