GR 64349

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Names

[ CAS No. ]:
137593-52-3

[ Name ]:
GR 64349

[Synonym ]:
1-Lithio-2-methylnaphthalin, lithium
1-lithio-2-methylnaphthalene

Chemical & Physical Properties

[ Density]:
1.31g/cm3

[ Boiling Point ]:
1342.8ºC at 760mmHg

[ Molecular Formula ]:
C42H68N10O11S

[ Molecular Weight ]:
921.11500

[ Flash Point ]:
765.9ºC

[ Exact Mass ]:
920.47900

[ PSA ]:
372.87000

[ LogP ]:
1.98680

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • boc-freidinger's lactam
  • N-(tert-butoxycarbonyl)-D-methionyl-L-leucine methyl ester
  • Fmoc-Val-OPfp
  • Fmoc-Phe-OPfp
  • Fmoc-Met-OH

DownStream

Articles

Endogenous modulation of excitatory amino acid responsiveness by tachykinin NK1 and NK2 receptors in the rat spinal cord.

Br. J. Pharmacol. 115(6) , 1013-9, (1995)

1. The effects of selective tachykinin (neurokinin, NK) NK1 and NK2 receptor antagonists have been examined on spinal neurones in alpha-chloralose anaesthetized, spinalized rats. They were tested for ...

Tachykinin receptor types: Classification and membrane signalling mechanisms.

Neurochem. Int. 18 , 149-165, (1991)

The use of selective agonists in both functional and binding studies has provided unequivocal evidence for the existence of three types of tachykinin receptor (NK(1), NK(2) and NK(3)); there is also p...

Receptor-selective, peptidase-resistant agonists at neurokinin NK-1 and NK-2 receptors: new tools for investigating neurokinin function.

Neuropeptides 19 , 127-135, (1991)

The pharmacological profiles of two novel neurokinin agonists have been investigated. delta Ava[L-Pro9,N-MeLeu10]SP(7-11) (GR73632) and [Lys3,Gly8-R-gamma-lactam-Leu9] NKA(3-10) (GR64349) are potent a...


More Articles

Related Compounds

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  • CID 169546377
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