5-cyclopropyl-8-fluoro-2-hydroxy-7-piperazin-1-ylpyrimido[1,6-a]benzimidazole-1,3-dione,hydrochloride

Names

[ Name ]:
5-cyclopropyl-8-fluoro-2-hydroxy-7-piperazin-1-ylpyrimido[1,6-a]benzimidazole-1,3-dione,hydrochloride

[Synonym ]:
5-cyclopropyl-8-fluoro-2-hydroxy-7-piperazin-1-ylpyrimido[1,6-a]benzimidazole-1,3-dione hydrochloride
5-Cyclopropyl-8-fluoro-2-hydroxy-7-piperazinopyrimido(1,6-a)benzimidazole-1,3-dione HCl
Pyrimido(1,6-a)benzimidazole-1,3(2H,5H)-dione,5-cyclopropyl-8-fluoro-2-hydroxy-7-(1-piperazinyl)-,monohydrochloride
5-cyclopropyl-8-fluoro-2-hydroxy-7-(1-piperazinyl)-pyrimido[1,6-a]benzimidazole-1,3(2H,5H)-dione hydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
627.2ºC at 760mmHg

[ Molecular Formula ]:
C₁₇H₁₉ClFN₅O₃

[ Molecular Weight ]:
395.81600

[ Flash Point ]:
333.1ºC

[ Exact Mass ]:
395.11600

[ PSA ]:
83.91000

[ LogP ]:
1.73260

[ Vapour Pressure ]:
1.35E-16mmHg at 25°C

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

1-Chloro-2,5-difluoro-4-nitrobenzene
N-cyclopropyl-4-fluoro-2-nitro-5-piperazin-1-ylaniline
1-acetyl-4-[5-(cyclopropylamino)-2-fluoro-4-nitrophenyl]piperazine
tert-butyl 4-[2-(benzyloxy)-5-cyclopropyl-8-fluoro-1,2,3,5-tetrahydro-1,3-dioxopyrimido[1,6-a]benzimidazol-7-yl]-1-piperazinecarboxylate
tert-butyl 4-[5-cyclopropyl-8-fluoro-1,2,3,5-tetrahydro-2-hydroxy-1,3-dioxopyrimido[1,6-a]benzimidazol-7-yl]-1-piperazinecarboxylate