D-(-)-Salicin

Suppliers

Names

[ CAS No. ]:
138-52-3

[ Name ]:
D-(-)-Salicin

[Synonym ]:
EINECS 205-331-6
Saligenin-β-δ-glucopyranoside
SALICOSIDE
(2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-[2-(hydroxymethyl)phenoxy]tetrahydro-2H-pyran-3,4,5-triol
2-(Hydroxymethyl)phenyl β-D-glucopyranoside
Salicyl alcohol-b-glucoside
2-(Hydroxymethyl)phenyl-β-D-glucopyranoside
2-(Hydroxymethyl)phenyl-beta-D-glucopyranoside
(2R,3S,4S,5R,6S)-2-(Hydroxyméthyl)-6-[2-(hydroxyméthyl)phénoxy]tétrahydro-2H-pyran-3,4,5-triol
Saligenin-β-D-glucopyranoside
(2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-(2-(hydroxymethyl)phenoxy)tetrahydro-2H-pyran-3,4,5-triol
Saligenin-b-D-glucopyranoside
o-(Hydroxymethyl)phenyl β-D-glucopyranoside
WHITE WILLOW
Salix alba L.
D(-)-Salicin
2-(Hydroxymethyl)phenyl-b-D-glucopyranoside
D-(−)-Salicin
D-(-)-Salicin
β-D-Glucopyranoside, 2-(hydroxymethyl)phenyl
a-Hydroxy-o-tolyl b-D-glucopyranoside
Salicin
Salicine
MFCD00006590
β-D-Glucopyranoside, 2- (hydroxymethyl)phenyl

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
549.1±50.0 °C at 760 mmHg

[ Melting Point ]:
196-202 °C

[ Molecular Formula ]:
C₁₃H₁₈O₇

[ Molecular Weight ]:
286.278

[ Flash Point ]:
285.9±30.1 °C

[ Exact Mass ]:
286.105255

[ PSA ]:
119.61000

[ LogP ]:
-1.85

[ Vapour Pressure ]:
0.0±1.6 mmHg at 25°C

[ Index of Refraction ]:
1.638

[ Storage condition ]:
Store at RT.

[ Water Solubility ]:
36 g/L (15 ºC), 250 g/L (60 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LZ5901700

CHEMICAL NAME :: beta-D-Glucopyranoside, 2-(hydroxymethyl)phenyl-

CAS REGISTRY NUMBER :: 138-52-3

LAST UPDATED :: 199706

DATA ITEMS CITED :: 2

MOLECULAR FORMULA :: C13-H18-O7

MOLECULAR WEIGHT :: 286.31

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 6,63,1954

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H317

[ Precautionary Statements ]:
P280

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R43

[ Safety Phrases ]:
S36/37-S37-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
LZ5901700

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Aspen defense chemicals influence midgut bacterial community composition of gypsy moth.

J. Chem. Ecol. 41(1) , 75-84, (2015)

Microbial symbionts are becoming increasingly recognized as mediators of many aspects of plant - herbivore interactions. However, the influence of plant chemical defenses on gut associates of insect h...

Development of a fast extraction method and optimization of liquid chromatography-mass spectrometry for the analysis of phenolic compounds in lentil seed coats.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 969 , 149-61, (2014)

A systematic set of optimization experiments was conducted to design an efficient extraction and analysis protocol for screening six different sub-classes of phenolic compounds in the seed coat of var...

Catechol, a bioactive degradation product of salicortin, reduces TNF-α induced ICAM-1 expression in human endothelial cells.

Planta Med. 77(10) , 1024-6, (2011)

The phenolic glucoside salicortin was isolated from a Willow bark extract, and its ability to reduce the TNF- α induced ICAM-1 expression (10 ng/mL, 30 min pretreatment with salicortin) was tested IN ...