N,N-Dimethyl-4-nitrosoaniline
Suppliers
Names
[ CAS No. ]:
138-89-6
[ Name ]:
N,N-Dimethyl-4-nitrosoaniline
[Synonym ]:
EINECS 205-343-1
p-nitrosodimethyl aniline
p-dimethylaminonitrosobenzene
p-Nitrosodimethylanilide
4-nitroso-N,N-di-methylaniline
MFCD00002063
N,N-dimethyl-p-nitrosoaniline
Paranitrosodimethylanilide
Benzenamine, N,N-dimethyl-4-nitroso-
p-Nitroso-N,N-dimethylaniline
N,N-Dimethyl-4-nitrosoaniline
4-Nitrosodimethylaniline
Accelerine
4-Nitroso-N,N-dimethylaniline
Chemical & Physical Properties
[ Density]:
1.0±0.1 g/cm3
[ Boiling Point ]:
258.7±23.0 °C at 760 mmHg
[ Melting Point ]:
85-87 °C(lit.)
[ Molecular Formula ]:
C8H10N2O
[ Molecular Weight ]:
150.178
[ Flash Point ]:
110.3±22.6 °C
[ Exact Mass ]:
150.079315
[ PSA ]:
32.67000
[ LogP ]:
2.02
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.529
[ Stability ]:
Stable. Incompatible with strong oxidizing agents, strong reducing agents, strong acids, acetic acid, acetic anhydride. Highly flammable (?)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BX7175000
- CHEMICAL NAME :
- Aniline, N,N-dimethyl-p-nitroso-
- CAS REGISTRY NUMBER :
- 138-89-6
- BEILSTEIN REFERENCE NO. :
- 0607293
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C8-H10-N2-O
- MOLECULAR WEIGHT :
- 150.20
- WISWESSER LINE NOTATION :
- ONR DN1&1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - species unspecified
- DOSE/DURATION :
- 650 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Kidney, Ureter, Bladder - hematuria
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 7300 mg/kg/1Y-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Blood - lymphoma, including Hodgkin's disease
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 10 ug/plate
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 8(Suppl 7),1,1986
Safety Information
[ Symbol ]:
GHS02, GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H251-H301-H315-H317-H319-H335
[ Precautionary Statements ]:
P235 + P410-P261-P280-P301 + P310-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges
[ Hazard Codes ]:
F:Highlyflammable;T:Toxic;
[ Risk Phrases ]:
R23/24/25;R33;R8
[ Safety Phrases ]:
S16-S26-S36/37-S45
[ RIDADR ]:
UN 1369 4.2/PG 2
[ WGK Germany ]:
3
[ RTECS ]:
BX7175000
[ Packaging Group ]:
II
[ Hazard Class ]:
4.2
[ HS Code ]:
2921430090
Synthetic Route
Customs
[ HS Code ]: 2921430090
[ Summary ]:
HS:2921430090 toluidines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%
Articles
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[Display omitted]
Regul Toxicol Pharmacol 72 , 578-85, (2015)
Previously, a non-animal screening approach was proposed for evaluating photosafety of cosmetic ingredients by means of in vitro photochemical and photobiochemical assays; however, complex cosmetic in...
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This study aimed to qualify photosafety screening on the basis of photochemical and pharmacokinetic (PK) data on dermally applied chemicals. Six benzophenone derivatives (BZPs) were selected as model ...