NKH477

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Names

[ CAS No. ]:
138605-00-2

[ Name ]:
NKH477

[Synonym ]:
(3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-Acetoxy-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-3-vinyldodecahydro-1H-benzo[f]chromen-6-yl N,N-dimethyl-β-alaninate hydrochloride (1:1)
colforsindapropatehydrochloride
Adehl
β-Alanine, N,N-dimethyl-, (3R,4aR,5S,6S,6aS,10S,10aR,10bS)-5-(acetyloxy)-3-ethenyldodecahydro-10,10b-dihydroxy-3,4a,7,7,10a-pentamethyl-1-oxo-1H-naphtho[2,1-b]pyran-6-yl ester, hydrochloride (1:1)
NKH 477
colforsin daropate hydrochloride
6-[3-(dimethylamino)propionyl]-forskolin,Colforsin dapropate hydrochloride,N,N-dimethyl
MKH 477

Chemical & Physical Properties

[ Boiling Point ]:
571.4ºC at 760mmHg

[ Molecular Formula ]:
C27H44ClNO8

[ Molecular Weight ]:
546.093

[ Flash Point ]:
176ºC

[ Exact Mass ]:
545.275574

[ PSA ]:
122.60000

[ LogP ]:
2.82450

[ Vapour Pressure ]:
5.29E-16mmHg at 25°C

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Symbol ]:

GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H300

[ Precautionary Statements ]:
P264-P301 + P310

[ Hazard Codes ]:
T

[ Safety Phrases ]:
28-36/37-45

[ RIDADR ]:
UN 2811 6.1 / PGII

[ RTECS ]:
AY5992600

Articles

Analysis of compartmentalized cAMP: a method to compare signals from differently targeted FRET reporters.

Methods Mol. Biol. 1071 , 59-71, (2014)

Förster resonance energy transfer (FRET)-based reporters are important tools to study the spatiotemporal compartmentalization of cyclic adenosine monophosphate (cAMP) in living cells. To increase the ...

Chemically induced pluripotent stem cells (CiPSCs): a transgene-free approach.

J. Mol. Cell Biol. 5(5) , 354-5, (2013)

Induced pluripotent stem cells (iPSCs) could be generated by a single gene Oct4 and chemical compounds, in which exogenous expression of Oct4 was indispensable for reprogramming. Recent advances in ch...

Activation of cAMP signaling attenuates impaired hepatic glucose disposal in aged male p21-activated protein kinase-1 knockout mice.

Endocrinology 155(6) , 2122-32, (2014)

p21-activated protein kinase-1 (Pak1) plays a role in insulin secretion and glucagon-like peptide-1 (GLP-1) production. Pak1(-/-) mice were found to carry a defect in ip pyruvate tolerance test (IPPTT...


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