Icatibant acetate

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Names

[ CAS No. ]:
138614-30-9

[ Name ]:
Icatibant acetate

[Synonym ]:
Icatibant acetate

Chemical & Physical Properties

[ Density]:
1.6g/cm3

[ Molecular Formula ]:
C₆₁H₉₃N₁₉O₁₅S

[ Molecular Weight ]:
1364.57000

[ Exact Mass ]:
1363.68000

[ PSA ]:
581.76000

[ LogP ]:
1.67610

[ Storage condition ]:
-20℃

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Contribution of endogenous bradykinin to fibrinolysis, inflammation, and blood product transfusion following cardiac surgery: a randomized clinical trial.

Clin. Pharmacol. Ther. 93(4) , 326-34, (2013)

Bradykinin increases during cardiopulmonary bypass (CPB) and stimulates the release of nitric oxide, inflammatory cytokines, and tissue-type plasminogen activator (t-PA), acting through its B2 recepto...

Interaction between bradykinin and natriuretic peptides via RGS protein activation in HEK-293 cells.

Am. J. Physiol. Cell Physiol. 303(12) , C1260-8, (2012)

In this study, the interaction of natriuretic peptides (NP) and bradykinin (BK) signaling pathways was identified by measuring membrane potential (V(m)) and intracellular Ca(2+) using the patch-clamp ...

Influence of kinin peptides on monocyte-endothelial cell adhesion.

J. Cell. Biochem. 115(11) , 1985-95, (2014)

Adhesion of leukocytes to vascular endothelium in response to proinflammatory mediators is an important component of the overall inflammatory reaction. In the current work, we used a retinoic acid-dif...

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