[(7R)-6-(5-chloropyridin-2-yl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate

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Names

[ CAS No. ]:
138680-08-7

[ Name ]:
[(7R)-6-(5-chloropyridin-2-yl)-5-oxo-7H-pyrrolo[3,4-b]pyrazin-7-yl] 4-methylpiperazine-1-carboxylate

[Synonym ]:
ZPC
R-(-)-zopiclone
Tocris-1094
Lopac-Z-4900
(R)-zolpiclone
(5R)-6-(5-chloropyridin-2-yl)-7-oxo-6,7-dihydro-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate
Zopiclone,(R)
(+)-6-(5-chloropyrid-2-yl)-5-(4-methylpiperazin-1-yl)carbonyloxy-7-oxo-6,7-dihydro-5H-pyrrolo[3-4-b]pyrazine
(-)-Zopiclone
(R)-6-(5-chloro-2-pyridinyl)-6,7-dihydro-7-oxo-5H-pyrrolo-[3,4-b] pyrazin-5-yl 4-methylpiperazine-1-carboxylate

Chemical & Physical Properties

[ Molecular Formula ]:
C17H17ClN6O3

[ Molecular Weight ]:
388.80800

[ Exact Mass ]:
388.10500

[ PSA ]:
91.76000

[ LogP ]:
1.50880

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • (R)-zopiclone N-acetyl-L-aspartate
  • Eszopiclone
  • (S)-(+)-6-(5-chloro-2-pyridinyl)-7-(4-methylpiperazin-1-yl-carbonyloxy)-6,7-dihydro-5h-pyrrolo[3,4-b]pyrazine-5-one D-(+)-malate
  • Zopiclone

DownStream

  • 6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-hydroxy-5H-pyrrolo[3,4-b]pyrazin-5-one
  • Zopiclone
  • Eszopiclone

Related Compounds

  • 6-[3-(benzyloxy)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-4-methylhexanoic acid
  • (2S,3R)-3-(benzyloxy)-2-{[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentyl]formamido}butanoic acid
  • (2S)-2-[(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-3,3-dimethylbutanoic acid
  • 2-[(3R)-3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)butanamido]-2-methylpentanoic acid
  • rac-2-{[(2R,3R)-3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxolan-2-yl]formamido}acetic acid
  • (2R)-1-[(2RS,3RS)-3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxolane-2-carbonyl]piperidine-2-carboxylic acid
  • (3S)-1-[(2RS,3RS)-3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxolane-2-carbonyl]piperidine-3-carboxylic acid
  • rac-1-({[(2R,3R)-3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxolan-2-yl]formamido}methyl)cyclobutane-1-carboxylic acid
  • rac-1-[(2R,3R)-3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxolane-2-carbonyl]-3-methylpyrrolidine-3-carboxylic acid
  • rac-3-[(2R,3R)-3-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]oxolane-2-amido]cyclopentane-1-carboxylic acid
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