1,N6-ETHENOADENINE

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Names

[ CAS No. ]:
13875-63-3

[ Name ]:
1,N6-ETHENOADENINE

[Synonym ]:
1H-imidazo[2,1-f]purine
1H-Imidazo(2,1-i)purine
ethenoadenine
1(3)H-imidazo[2,1-i]purine
1,N6-Ethenoadenine
3H-IMIDAZO[2,1-I]PURINE

Chemical & Physical Properties

[ Density]:
1.78g/cm3

[ Molecular Formula ]:
C7H5N5

[ Molecular Weight ]:
159.14800

[ Exact Mass ]:
159.05400

[ PSA ]:
58.87000

[ LogP ]:
0.60560

[ Index of Refraction ]:
1.956

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933990090

Precursor & DownStream

Precursor

  • N6-Etheno 2'-deoxyadenosine

DownStream

  • N6-Etheno 2'-deoxyadenosine

Customs

[ HS Code ]: 2933990090

[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Measurement of urinary excretion of 5-hydroxymethyluracil in human by GC/NICI/MS: correlation with cigarette smoking, urinary TBARS and etheno DNA adduct.

Toxicol. Lett. 155(3) , 403-10, (2005)

5-Hydroxymethyluracil (5-HMU) is derived from radiation in addition to endogenous oxidative DNA damage and it is one of the most abundant DNA adducts. Human 5-HMU-DNA-glycosylase has been shown to rep...

Highly mutagenic exocyclic DNA adducts are substrates for the human nucleotide incision repair pathway.

PLoS ONE 7(12) , e51776, (2012)

Oxygen free radicals induce lipid peroxidation (LPO) that damages and breaks polyunsaturated fatty acids in cell membranes. LPO-derived aldehydes and hydroxyalkenals react with DNA leading to the form...

Magnesium, essential for base excision repair enzymes, inhibits substrate binding of N-methylpurine-DNA glycosylase.

J. Biol. Chem. 281(40) , 29525-32, (2006)

N-Methylpurine-DNA glycosylase (MPG) initiates base excision repair in DNA by removing a wide variety of alkylated, deaminated, and lipid peroxidation-induced purine adducts. MPG activity and other DN...


More Articles

Related Compounds

  • Nicotinamide1,N6-EthenoadenineDinucleotide
  • Nicotinamide 1,N6-ethenoadenine dinucleotide phosphate sodium salt
  • 1,N6-Ethenoadenosine
  • [3-hydroxy-2,2-dimethyl-4-oxo-4-[[3-oxo-3-(2-sulfanylethylamino)propyl]amino]butyl] [hydroxy-[(4-hydroxy-5-imidazo[2,1-f]purin-3-yl-3-phosphonooxyoxolan-2-yl)methoxy]phosphoryl] hydrogen phosphate,lithium
  • 1,n6-ethenoadenosine-5'-diphosphate sodium salt
  • 1,n6-ethenoadenosine 5'-monophosphate sodium salt
  • O-[2-(2,3-dihydro-1,4-benzodioxin-6-yl)propan-2-yl]hydroxylamine
  • 1-(3,5-Difluoro-2-hydroxyphenyl)cyclopropane-1-carbaldehyde
  • 1-[4-(Dimethylcarbamoyl)phenyl]-2,2-difluorocyclopropane-1-carboxylic acid
  • 1-{[2-Fluoro-4-(trifluoromethyl)phenyl]methyl}cyclopropane-1-carboxylic acid
  • NADPH xsodium salt
  • 4-[1-(Methylsulfanyl)propan-2-yl]piperidine
  • 2-Amino-2-[4-(methoxymethyl)phenyl]propan-1-ol
  • 2-Oxaspiro[4.4]nonane-4-carboxylic acid
  • 1,1,1-Trifluoro-3-(2-methanesulfonylphenyl)propan-2-ol
  • 3-Amino-1-[3-(propan-2-yl)phenyl]cyclobutane-1-carboxylic acid
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