3-(2-methylpiperidin-1-yl)propyl 4-cyclohexyloxybenzoate

Names

[ CAS No. ]:
139-62-8

[ Name ]:
3-(2-methylpiperidin-1-yl)propyl 4-cyclohexyloxybenzoate

[Synonym ]:
Benzoic acid,p-(cyclohexyloxy)-,3-(2-methylpiperidino)propyl ester
4-cyclohexyloxy-benzoic acid-[3-(2-methyl-piperidino)-propyl ester]
Ciclometicaina [INN-Spanish]
Surfacaine
Cainasurfa
Cyclomethycainum [INN-Latin]
Surfathesin
3-(2-methylpiperidin-1-yl)propyl 4-(cyclohexyloxy)benzoate
Topocaine
cyclomethylcaine
Cyclomethycain
Cyclomethycaine
4-Cyclohexyloxy-benzoesaeure-[3-(2-methyl-piperidino)-propylester]
Benzoic acid,4-(cyclohexyloxy)-,3-(2-methyl-1-piperidinyl)propyl ester

Chemical & Physical Properties

[ Density]:
1.056g/cm3

[ Boiling Point ]:
486.4ºC at 760mmHg

[ Molecular Formula ]:
C22H33NO3

[ Molecular Weight ]:
359.50200

[ Flash Point ]:
248ºC

[ Exact Mass ]:
359.24600

[ PSA ]:
38.77000

[ LogP ]:
4.75730

[ Vapour Pressure ]:
1.3E-09mmHg at 25°C

[ Index of Refraction ]:
1.525

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DG5679000
CHEMICAL NAME :
Benzoic acid, p-(cyclohexyloxy)-, 3-(2-methylpiperidino)propyl ester
CAS REGISTRY NUMBER :
139-62-8
BEILSTEIN REFERENCE NO. :
0293510
LAST UPDATED :
199612
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C22-H33-N-O3
MOLECULAR WEIGHT :
359.56
WISWESSER LINE NOTATION :
T6NTJ B1 A3OVR DO- AL6TJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :
DNA adduct
TEST SYSTEM :
Bacteria - Escherichia coli
DOSE/DURATION :
5 umol/L
REFERENCE :
MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 89,95,1981 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83097 No. of Facilities: 28 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 28 (estimated)

Safety Information

[ HS Code ]:
2933399090

Precursor & DownStream

Precursor

  • 2-Pipecoline
  • Cyclohexane, iodo-
  • 1-(3-chloropropyl)-2-methylpiperidine
  • 4-(Cyclohexyloxy)benzoic acid
  • Isopropanol
  • Bromocyclohexane
  • Ethylparaben

DownStream

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Related Compounds

  • (2R)-6-(1H-1,3-benzodiazol-2-yl)hexan-2-amine
  • 4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
  • 1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
  • 2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
  • 1H-3-Benzazepin-7-ol, 8-chloro-2,3,4,5-tetrahydro-5-(3-iodophenyl)-3-methyl-, (S)-
  • tert-butyl N-[2-amino-1-(2-methylcyclopropyl)ethyl]carbamate
  • (4-Methyl-tetrahydro-furan-2-yl)-methanol
  • 3-(2,4-Difluoro-5-methylphenyl)-2,2-difluoropropanoic acid
  • N-(1-cyanocyclopentyl)-2-[4-(4-fluorobenzenesulfonyl)-1,4-diazepan-1-yl]acetamide
  • 4,5,6,7-Tetrahydrobenzo[d]isoxazole-3-carbaldehyde