1-ethyl-3-(5-nitro-1,3-thiazol-2-yl)urea
Names
[ CAS No. ]:
139-94-6
[ Name ]:
1-ethyl-3-(5-nitro-1,3-thiazol-2-yl)urea
[Synonym ]:
N-ethyl-N'-(5-nitro-thiazol-2-yl)-urea
1-Ethyl-3-(5-nitrothiazol-2-yl)urea
Hepzide 30
N-Aethyl-N'-(5-nitro-thiazol-2-yl)-harnstoff
EINECS 205-387-1
Nithiazide
Nithiazid
1-Ethyl-3-(5-nitro-2-thiazolyl)harnstoff
Hepzide
Chemical & Physical Properties
[ Density]:
1.518g/cm3
[ Melting Point ]:
228ºC
[ Molecular Formula ]:
C6H8N4O3S
[ Molecular Weight ]:
216.21800
[ Exact Mass ]:
216.03200
[ PSA ]:
128.08000
[ LogP ]:
2.17980
[ Index of Refraction ]:
1.647
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YT3500000
- CHEMICAL NAME :
- Urea, 1-ethyl-3-(5-nitro-2-thiazolyl)-
- CAS REGISTRY NUMBER :
- 139-94-6
- BEILSTEIN REFERENCE NO. :
- 0218168
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 9
- MOLECULAR FORMULA :
- C6-H8-N4-O3-S
- MOLECULAR WEIGHT :
- 216.24
- WISWESSER LINE NOTATION :
- T5N CSJ BMVM2 ENW
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2150 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 41 gm/kg/94W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Skin and Appendages - tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 395 gm/kg/94W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Liver - tumors
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 75 ug/plate
- REFERENCE :
- ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 5(Suppl 1),3,1983 *** REVIEWS *** IARC Cancer Review:Animal Limited Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 31,179,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 31,179,1983 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987
Safety Information
[ HS Code ]:
2934100090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2934100090
[ Summary ]:
2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%