KN-93

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Names

[ CAS No. ]:
139298-40-1

[ Name ]:
KN-93

[Synonym ]:
MFCD00236424
N-[2-({[(2E)-3-(4-Chlorophenyl)prop-2-en-1-yl](methyl)amino}methyl)phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide
N-[2-({[(2E)-3-(4-Chlorophenyl)-2-propen-1-yl](methyl)amino}methyl)phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide
KN-93,WATER-SOLUBLE
N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulfonamide
METHOXYBENZENE-SULFONAMIDE
N-[2-[[[3-(4-Chlorophenyl)-2-propenyl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenzenesulphonamide
N-[2-N-4-CHLOROCINNAMYL-N-METHYLAMINOMETHYLPHENYL]-N-[2-HYDROXYETHYL]-4-METHOXYBENZENESULFONAMIDE
2-[N-(2-HYDROXYETHYL)-N-(4-METHOXYBENZENESULFONYL)]AMINO-N-(4-CHLOROCINNAMYL)-N-METHYLBENZYLAMINE
Benzenesulfonamide, N-[2-[[[(2E)-3-(4-chlorophenyl)-2-propen-1-yl]methylamino]methyl]phenyl]-N-(2-hydroxyethyl)-4-methoxy-
N-[2-[N-(4-Chlorocinnamyl)-N-methylaminomethyl]phenyl]-N-(2-hydroxyethyl)-4-methoxybenze

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
657.6±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C26H29ClN2O4S

[ Molecular Weight ]:
501.038

[ Flash Point ]:
351.5±34.3 °C

[ Exact Mass ]:
500.153656

[ PSA ]:
78.46000

[ LogP ]:
4.71

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.627

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
DMSO: 1 mg/mL

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Ca(2+) permeation and/or binding to CaV1.1 fine-tunes skeletal muscle Ca(2+) signaling to sustain muscle function.

Skelet. Muscle 5 , 4, (2015)

Ca(2+) influx through CaV1.1 is not required for skeletal muscle excitation-contraction coupling, but whether Ca(2+) permeation through CaV1.1 during sustained muscle activity plays a functional role ...

Transient Receptor Potential Canonical 1 (TRPC1) Channels as Regulators of Sphingolipid and VEGF Receptor Expression: IMPLICATIONS FOR THYROID CANCER CELL MIGRATION AND PROLIFERATION.

J. Biol. Chem. 290 , 16116-31, (2015)

The identity of calcium channels in the thyroid is unclear. In human follicular thyroid ML-1 cancer cells, sphingolipid sphingosine 1-phosphate (S1P), through S1P receptors 1 and 3 (S1P1/S1P3), and VE...

Modulation of P2X4/P2X7/Pannexin-1 sensitivity to extracellular ATP via Ivermectin induces a non-apoptotic and inflammatory form of cancer cell death.

Sci. Rep. 5 , 16222, (2015)

Overexpression of P2X7 receptors correlates with tumor growth and metastasis. Yet, release of ATP is associated with immunogenic cancer cell death as well as inflammatory responses caused by necrotic ...


More Articles

Related Compounds

  • KN-93 Phosphate
  • KN-93 phosphate
  • KN-93 hydrochloride
  • KN-92
  • KN-92
  • KN-NAc-His
  • 3-(Pyrazolyl)pyruvic acid
  • 4-Bromo-2-methyl-6-(trifluoromethyl)benzamide
  • 3,9-Diazaspiro[5.5]undec-3-yl(2-fluorophenyl)methanone hydrochloride
  • 3,9-Diazaspiro[5.5]undecan-3-yl(phenyl)methanone;hydrochloride
  • 4-Amino-3-bromo-6-chloro-2,8-dimethylquinoline
  • 4-Bromo-3-iodo-7-methylquinoline
  • 2,3-Dihydro-2-[(4-methoxyphenyl)methyl]-3,3-dimethyl-5-(4-pyrimidinylamino)-1h-isoindol-1-one
  • 4-Bromo-3-iodo-8-methoxyquinoline
  • 4-Amino-3-bromo-6-methoxy-2-methylquinoline
  • 4-Amino-3-bromo-8-chloro-2-methylquinoline
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