CGP 52432

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Names

[ CAS No. ]:
139667-74-6

[ Name ]:
CGP 52432

[Synonym ]:
Tocris-1246
MFCD00041095
[3-[[(3,4-Dichlorophenyl)methyl]amino]propyl](diethoxymethyl)-phosphinic acid
CGP52432

Chemical & Physical Properties

[ Density]:
1.258g/cm3

[ Boiling Point ]:
544.4ºC at 760mmHg

[ Molecular Formula ]:
C15H24Cl2NO4P

[ Molecular Weight ]:
384.23500

[ Flash Point ]:
283.1ºC

[ Exact Mass ]:
383.08200

[ PSA ]:
77.60000

[ LogP ]:
4.49100

[ Vapour Pressure ]:
1.1E-12mmHg at 25°C

[ Index of Refraction ]:
1.524

[ Storage condition ]:
2-8℃

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

Correlated changes in NMDA receptor phosphorylation, functional activity, and sedation by chronic ethanol consumption.

J. Neurochem. 115(5) , 1112-22, (2010)

Alcohol abuse leads to tolerance, dependence, and memory impairments that involve excitatory glutamatergic NMDA synaptic transmission. The NMDA receptor (NMDAR) is known to undergo activity-dependent ...

Presynaptic mGlu7 receptors control GABA release in mouse hippocampus.

Neuropharmacology 66 , 215-24, (2013)

The functional role of presynaptic release-regulating metabotropic glutamate type 7 (mGlu7) receptors in hippocampal GABAergic terminals was investigated. Mouse hippocampal synaptosomes were preloaded...

Hippocampal Pyramidal Neurons Comprise Two Distinct Cell Types that Are Countermodulated by Metabotropic Receptors

Neuron 76(4) , 776-89, (2012)

Relating the function of neuronal cell types to information processing and behavior is a central goal of neuroscience. In the hippocampus, pyramidal cells in CA1 and the subiculum process sensory and ...


More Articles

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