Benzyl chloroacetate
Suppliers
Names
[ CAS No. ]:
140-18-1
[ Name ]:
Benzyl chloroacetate
[Synonym ]:
benzyl monochloroacetate
chloroacetic acid benzyl ester
Acetic acid, 2-chloro-, phenylmethyl ester
Acetic acid,chloro-,phenylmethyl ester
MFCD00157062
Benzyl α-chloroacetate
Benzyl monochloracetate
Benzyl chloroacetate
chloroacetic acid phenylmethyl ester
Monochloroacetate
EINECS 205-400-0
BENZYL 2-CHLOROACETATE
Acetic acid,chloro-,benzyl ester
phenylmethyl 2-chloroacetate
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
252.8±15.0 °C at 760 mmHg
[ Melting Point ]:
90ºC
[ Molecular Formula ]:
C9H9ClO2
[ Molecular Weight ]:
184.620
[ Flash Point ]:
117.9±15.8 °C
[ Exact Mass ]:
184.029114
[ PSA ]:
26.30000
[ LogP ]:
2.20
[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C
[ Index of Refraction ]:
1.525
[ Water Solubility ]:
insoluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AF8750000
- CHEMICAL NAME :
- Acetic acid, chloro-, benzyl ester
- CAS REGISTRY NUMBER :
- 140-18-1
- BEILSTEIN REFERENCE NO. :
- 2091502
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C9-H9-Cl-O2
- MOLECULAR WEIGHT :
- 184.63
- WISWESSER LINE NOTATION :
- G1VO1R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CBCCT* "Summary Tables of Biological Tests," National Research Council Chemical-Biological Coordination Center. (National Academy of Science Library, 2101 Constitution Ave., NW, Washington, DC 20418) Volume(issue)/page/year: 8,99,1956
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
AF8750000
[ HS Code ]:
2915400090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2915400090
[ Summary ]:
2915400090 mono-, di- or trichloroacetic acids, their salts and esters
Articles
J. Med. Chem. 20(5) , 660-3, (1977)
The synthesis of monoesters (P and C) of phosphonoacetic acid (PA) is given. The carboxyl esters were prepared by two methods: the reaction of chloroacetates with tris(trimethylsilyl) phosphite, follo...
Influence of the substrate structure on carboxypeptidase Y catalyzed peptide bond formation. Breddam K, et al.Carlsberg Res. Commun. 45(5) , 361-67, (1980)
Stereoselective total syntheses of the (±)-di-O-methyl ethers of agatharesinol, sesquirin-A, and hinokiresinol, and of (±)-tri-O-methylsequirin-E, characteristic norlignans of coniferae. Beracierta AP and Whiting DA.
J. Chem. Soc. Perkin Trans. I 10 , 1257-63, (1978)