2-Methyl-5-vinylpyridine

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Names

[ CAS No. ]:
140-76-1

[ Name ]:
2-Methyl-5-vinylpyridine

[Synonym ]:
5-20-06-00218 (Beilstein Handbook Reference)
2-methyl-5-vinyl pyridine
Pyridine, 5-ethenyl-2-methyl-
EINECS 205-432-5
Pyridine, 2-methyl-5-vinyl
5-vinyl-2-methylpyridine
2-Methyl-5-vinylpridine
2,5-Methylvinylpyridine
Pyridine,2-methyl-5-vinyl
5-Ethenyl-2-methypyridine
2-Methyl-5-vinyl-pyridin
5-Vinyl-2-picoline
2-Picoline,5-vinyl
methyl vinyl pyridine
5-ethenyl-2-methylpyridine
Pyridine,5-ethenyl-2-methyl
6-methyl-3-vinylpyridine
2-Methyl-5-vinylpyridine

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
175.5±9.0 °C at 760 mmHg

[ Melting Point ]:
180 °C (dec.)(lit.)

[ Molecular Formula ]:
C8H9N

[ Molecular Weight ]:
119.164

[ Flash Point ]:
56.6±10.9 °C

[ Exact Mass ]:
119.073502

[ PSA ]:
12.89000

[ LogP ]:
1.92

[ Vapour Pressure ]:
1.5±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.555

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UT2975000
CHEMICAL NAME :
Pyridine, 5-ethenyl-2-methyl-
CAS REGISTRY NUMBER :
140-76-1
BEILSTEIN REFERENCE NO. :
0106229
LAST UPDATED :
199712
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C8-H9-N
MOLECULAR WEIGHT :
119.18
WISWESSER LINE NOTATION :
T6NJ B1 E1U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: OTS0546451 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1300 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
189 mg/m3/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,88,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1290 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,88,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
775 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,88,1982
TYPE OF TEST :
LC50 - Lethal concentration, 50 percent kill
ROUTE OF EXPOSURE :
Inhalation
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
213 mg/m3/2H
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,88,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
532 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GMAT "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982 Volume(issue)/page/year: -,88,1982
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
800 uL/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - species unspecified
DOSE/DURATION :
1250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 39(4),86,1974 *** OCCUPATIONAL EXPOSURE LIMITS *** OEL-RUSSIA:STEL 2 mg/m3;Skin JAN 1993

Safety Information

[ Hazard Codes ]:
T+

[ RIDADR ]:
2810

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)

[ HS Code ]:
2933399090

Synthetic Route

Precursor & DownStream

Precursor

  • 5-Bromo-2-picoline
  • (6-Butyl-5-decen-5-yl)-λ2-stannane
  • 2-Methyl-5-formylpyridine
  • Methyltriphenylphosphonium bromide
  • 5-Ethyl-2-methylpyridine

DownStream

  • Latrepirdine
  • 6-Methylnicotinic acid
  • 2-Methyl-5-formylpyridine
  • [2-acetyloxy-2-(2,2-dimethyl-6-phenylmethoxy-3a,5,6,6a-tetrahydrofuro[2,3-d][1,3]dioxol-5-yl)ethyl] acetate
  • 6-Methylnicotinamide
  • 2-ethyl-8-methyl-5-[2-(6-methylpyridin-3-yl)ethyl]-3,4-dihydro-1H-pyrido[4,3-b]indole
  • 6-Methyl-3-pyridineethanol
  • 5-Ethyl-2-methylpyridine
  • 1-(6-METHYL-PYRIDIN-3-YL)-ETHANOL
  • 2,5-Pyridinedicarboxylic acid

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%


Related Compounds

  • 2-Methyl-5-vinylpyridine
  • 2-Methyl-5-vinylpyridine
  • 3-Ethyl-2-methyl-5-vinylpyridine
  • poly-2-methyl-5-vinylpyridine picrate
  • 2-methyl-3-hydroxy-4-mercaptomethyl-5-vinylpyridine hydrochloride
  • 2-methyl-5-(methylthio)-3-phenylfuran