Cyanoacetohydrazide
Suppliers
Names
[ CAS No. ]:
140-87-4
[ Name ]:
Cyanoacetohydrazide
[Synonym ]:
UNII-40H59YCS67
Cyacetacide
EINECS 205-437-2
Armazal
Cyanoacetylhydrazine
Dictycide
Cyanoacetic Acid Hydrazide
MFCD00007611
Neohydrazid
Cyanoacetic Hydrazide
a-Cyanoacetohydrazide
Dictyzide
2-Cyanoacetohydrazide
Hidacian
Acetic acid, 2-cyano-, hydrazide
Leandin
Malononitrile hydrazide
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
405.6±28.0 °C at 760 mmHg
[ Melting Point ]:
108-110 °C(lit.)
[ Molecular Formula ]:
C3H5N3O
[ Molecular Weight ]:
99.091
[ Flash Point ]:
199.1±24.0 °C
[ Exact Mass ]:
99.043259
[ PSA ]:
78.91000
[ LogP ]:
-2.16
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.480
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- AG4200000
- CHEMICAL NAME :
- Acetic acid, cyano-, hydrazide
- CAS REGISTRY NUMBER :
- 140-87-4
- BEILSTEIN REFERENCE NO. :
- 1751498
- LAST UPDATED :
- 199707
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C3-H5-N3-O
- MOLECULAR WEIGHT :
- 99.11
- WISWESSER LINE NOTATION :
- ZMV1CN
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CLDND* Compilation of LD50 Values of New Drugs. (J.R. MacDougal, Dept. of National Health and Welfare, Food and Drug Divisions, 35 John St., Ottawa, Ont., Canada)
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 100 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Subcutaneous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 228 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- ABMGAJ Acta Biologica et Medica Germanica. (Berlin, Ger. Dem. Rep.) V.1-41, 1958-82. For publisher information, see BBIADT. Volume(issue)/page/year: 21,635,1968
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301-H312-H315-H319-H332-H335
[ Precautionary Statements ]:
P261-P280-P301 + P310-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves
[ Hazard Codes ]:
Xn: Harmful;
[ Risk Phrases ]:
R20/21/22;R36/37/38
[ Safety Phrases ]:
S26-S28-S36/37/39-S45
[ RIDADR ]:
UN 2811 6.1/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
AG4200000
[ Packaging Group ]:
I; II; III
[ Hazard Class ]:
6.1
[ HS Code ]:
2928000090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2928000090
[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%
Articles
Acta Crystallogr. A 49 ( Pt 1) , 10-22, (1993)
For molecular crystals, a procedure is proposed for interpreting experimentally determined atomic mean square anisotropic displacement parameters (ADPs) in terms of the overall molecular vibration tog...
Arch. Pharm. (Weinheim) 339(1) , 14-23, (2006)
Two new acetylpyridinehydrazones derived from cyanoacetic acid hydrazide have been synthesized namely: cyanoacetic acid (1-pyridin-3 or 4-yl-ethylidene) hydrazides (1a,b). and some derived ring system...
Arch. Pharm. Res. 24(5) , 377-84, (2001)
The reaction of either Digitoxin or Digoxin with cyanoacetic acid hydrazide gave the hydrazone derivatives 3a and 3b respectively. The reactivity of the latter products towards chemical reagents was s...