Amlodipine Dimethyl Ester

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Names

[ CAS No. ]:
140171-66-0

[ Name ]:
Amlodipine Dimethyl Ester

[Synonym ]:
Dimethyl 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate
dimethylamlodipine
Amlodipine Dimethyl Ester
UNII-5TQ5PD1804
UNII:5TQ5PD1804
3,5-Pyridinedicarboxylic acid, 2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-, dimethyl ester
Amlodipine Impurity 6

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
516.6±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C19H23ClN2O5

[ Molecular Weight ]:
394.849

[ Flash Point ]:
266.2±30.1 °C

[ Exact Mass ]:
394.129547

[ PSA ]:
99.88000

[ LogP ]:
3.63

[ Vapour Pressure ]:
0.0±1.3 mmHg at 25°C

[ Index of Refraction ]:
1.550

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

  • Benzenesulfonic acid
  • Methyl acetoacetate
  • 2-Chlorobenzaldehyde
  • Methyl (Z)-3-aminocrotonate
  • 4-[2-(1,3-Dihydro-1,3-dioxo-2H-isoindol-2-yl)ethoxy]-3-oxobutanoic Acid Methyl Ester

DownStream

Related Compounds

  • cosalane dimethyl ester
  • dimethyl (2R)-2-[[4-[2-(2-amino-4-oxo-1,7-dihydropyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]amino]pentanedioate
  • Phosphoricacid, dimethyl ester, thorium(4+) salt (8CI)
  • Raloxifene dimethyl ester hydrochloride
  • dimethylether dimethyl ester of thomasidioic acid
  • narcissiflorine dimethyl ester
  • N-(1,3-benzothiazol-2-yl)-2-(2,4-dioxo-4a,5,6,7,8,8a-hexahydro-1H-quinazolin-3-yl)butanamide
  • N-(1,3-benzodioxol-5-yl)-6-(2,4-dioxo-4aH-quinazolin-3-yl)hexanamide
  • 4-(2,4-dioxo-4aH-quinazolin-3-yl)-N-pyridin-2-ylbutanamide
  • 2-(4,6-dimethyl-1,3-benzothiazol-2-yl)-1-(4-ethoxy-3-methoxyphenyl)-7-fluoro-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • 2-(2,4-dioxo-4a,5,6,7,8,8a-hexahydro-1H-quinazolin-3-yl)-N-pyridin-3-ylbutanamide
  • 3-[6-(4-benzylpiperidin-1-yl)-6-oxohexyl]-4aH-quinazoline-2,4-dione
  • 3-[1-[4-(4-fluorophenyl)piperazin-1-yl]-1-oxobutan-2-yl]-4a,5,6,7,8,8a-hexahydro-1H-quinazoline-2,4-dione
  • 7-chloro-1-(3-fluorophenyl)-2-pyridin-2-yl-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • 2-(1,3-benzothiazol-2-yl)-1-phenyl-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
  • 7-chloro-6-methyl-2-(6-methylpyridin-2-yl)-1-phenyl-4a,5,6,7,8,8a-hexahydro-1H-chromeno[2,3-c]pyrrole-3,9-dione
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