ACTINOMYCIN E2

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Names

[ CAS No. ]:
1402-42-2

[ Name ]:
ACTINOMYCIN E2

[Synonym ]:
Actinomycin E2
Actinomycin D,2(sup A)-D-alloisoleucine-5(sup A)-(N-methylisoleucine)-5(sup B)-(N-methylisoleucine)

Chemical & Physical Properties

[ Density]:
1.38g/cm3

[ Boiling Point ]:
1395.6ºC at 760mmHg

[ Molecular Formula ]:
C66H94N12O16

[ Molecular Weight ]:
1311.52000

[ Flash Point ]:
797.8ºC

[ Exact Mass ]:
1310.69000

[ PSA ]:
359.98000

[ LogP ]:
3.93400

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.644

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
AU1578500
CHEMICAL NAME :
Actinomycin D, 2(sup A)-D-alloisoleucine-5(sup A)-(N-methylisoleucine)-5(sup B)-(N- methylisoleucine)-
CAS REGISTRY NUMBER :
1402-42-2
LAST UPDATED :
198211
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C66-H94-N12-O16
MOLECULAR WEIGHT :
1311.72

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(2),67,1980

Related Compounds

  • actinomycin D-dATGCAT complex
  • Actinomycin D Lactam
  • actinomycin-A5-oic-D acid
  • actinomycin IV
  • 4,6-dimethyl-2,3-dioxo-9-N-[6,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-7-yl]-1-N-[7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan
  • 2-amino-7-ethoxy-4,6-dimethyl-3-oxo-1-N,9-N-bis[7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide
  • 1-(Cyclopropylmethyl)-1h-indazol-6-amine
  • 2-{3-[({[(1-methyl-1H-imidazol-2-yl)(phenyl)methyl]carbamoyl}methyl)sulfanyl]-5-propyl-4H-1,2,4-triazol-4-yl}acetic acid
  • 1-heptyl-1H-indazol-6-amine
  • N-[1-(1,3-Benzodioxol-5-yl)ethyl]-4-[[(E)-2-phenylethenyl]sulfonylamino]benzamide
  • 3-[4,6-dimethyl-2-(methylsulfanyl)pyrimidin-5-yl]-N-[3-(1-phenylethoxy)propyl]propanamide
  • 2-[(6-Methoxypyridin-3-yl)amino]-1-(morpholin-4-yl)propan-1-one
  • 6-Methoxy-2-methyl-1H-indol-5-ol
  • N-(4-acetylphenyl)-2-[4-[(2-phenyl-1,3-thiazol-4-yl)methyl]piperazin-1-yl]propanamide
  • CID 42930693
  • CID 42930694
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