Amphomycin

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Names

[ CAS No. ]:
1402-82-0

[ Name ]:
Amphomycin

Chemical & Physical Properties

[ Density]:
1.37g/cm3

[ Boiling Point ]:
1693.3ºC at 760 mmHg

[ Molecular Formula ]:
C58H91N13O20

[ Molecular Weight ]:
1290.42000

[ Flash Point ]:
977.9ºC

[ Exact Mass ]:
1289.65000

[ PSA ]:
506.84000

[ LogP ]:
0.52660

[ Vapour Pressure ]:
0mmHg at 25°C

[ Index of Refraction ]:
1.599

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
BU2100000
CHEMICAL NAME :
Amphomycin
CAS REGISTRY NUMBER :
1402-82-0
LAST UPDATED :
199109

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),317,1980
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
233 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CNCRA6 Cancer Chemotherapy Reports. (Bethesda, MD) V.1-52, 1959-68. For publisher information, see CTRRDO. Volume(issue)/page/year: 30,9,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
178 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85FZAT "Index of Antibiotics from Actinomycetes," Umezawa, H. et al., eds., Tokyo, Univ. of Tokyo Press, 1967 Volume(issue)/page/year: -,131,1967

Related Compounds

  • Sodium amphomycin
  • 4-methyl-4-(1-methyl-1H-pyrazol-3-yl)pyrrolidin-2-one
  • 3-(3-Hydroxybutyl)oxane-3-carbaldehyde
  • 1-benzyl-5-(propan-2-yl)-1H-1,2,3-triazole-4-carbothioamide
  • 5-ethyl-1-[(4-fluorophenyl)methyl]-1H-1,2,3-triazole-4-carbothioamide
  • 5-ethyl-1-[(2-fluorophenyl)methyl]-1H-1,2,3-triazole-4-carbothioamide
  • Methyl 4-(1-hydroxycyclohexyl)thiane-4-carboxylate
  • 4-Amino-1-ethyl-5-(1-methoxy-2-methylpropan-2-yl)pyrrolidin-2-one
  • 1-(2,2-Dimethylpropyl)cyclobutane-1-carbaldehyde
  • 3-(3-Methoxy-1,2-thiazol-4-yl)-2,2-dimethylpropanal
  • 2-(Ethoxymethyl)bicyclo[2.2.1]heptane-2-carbaldehyde
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