KT-109
Suppliers
Names
[ CAS No. ]:
1402612-55-8
[ Name ]:
KT-109
[Synonym ]:
(2-Benzyl-1-piperidinyl)[4-(4-biphenylyl)-1H-1,2,3-triazol-1-yl]methanone
Methanone, (4-[1,1'-biphenyl]-4-yl-1H-1,2,3-triazol-1-yl)[2-(phenylmethyl)-1-piperidinyl]-
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
637.3±53.0 °C at 760 mmHg
[ Molecular Formula ]:
C27H26N4O
[ Molecular Weight ]:
422.522
[ Flash Point ]:
339.3±30.9 °C
[ Exact Mass ]:
422.210663
[ LogP ]:
5.23
[ Vapour Pressure ]:
0.0±1.9 mmHg at 25°C
[ Index of Refraction ]:
1.653
[ Storage condition ]:
2-8°C
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H413
[ Precautionary Statements ]:
P301 + P312 + P330
[ Hazard Codes ]:
Xn
[ RIDADR ]:
NONH for all modes of transport
Articles
Nat. Chem. Biol. 8(12) , 999-1007, (2012)
The endocannabinoid 2-arachidonoylglycerol (2-AG) is biosynthesized by diacylglycerol lipases DAGLα and DAGLβ. Chemical probes to perturb DAGLs are needed to characterize endocannabinoid function in b...
J. Med. Chem. 56(21) , 8257-69, (2013)
We have previously shown that 1,2,3-triazole ureas (1,2,3-TUs) act as versatile class of irreversible serine hydrolase inhibitors that can be tuned to create selective probes for diverse members of th...
J. Biol. Chem. 289(3) , 1491-504, (2014)
Perturbation of calcium signaling that occurs during cell injury and disease, promotes cell death. In mouse lung fibroblasts A23187 triggered mitochondrial permeability transition pore (MPTP) formatio...