PFI-1

Suppliers

Names

[ Name ]:
PFI-1

[Synonym ]:
2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydro-6-quinazolinyl)benzenesulfonamide
Benzenesulfonamide, 2-methoxy-N-(1,2,3,4-tetrahydro-3-methyl-2-oxo-6-quinazolinyl)-
QCR-192
PFI-1
CS-1362
PF-6405761

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Molecular Formula ]:
C₁₆H₁₇N₃O₄S

[ Molecular Weight ]:
347.389

[ Exact Mass ]:
347.093964

[ PSA ]:
96.12000

[ LogP ]:
0.53

[ Appearance of Characters ]:
white to beige

[ Index of Refraction ]:
1.628

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
DMSO: ≥10mg/mL

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

Articles

The BET bromodomain inhibitor, JQ1, facilitates c-FLIP degradation and enhances TRAIL-induced apoptosis independent of BRD4 and c-Myc inhibition.

Oncotarget 6 , 34669-79, (2015)

Inhibition of BET bromodomains (BRDs) has emerged as a promising cancer therapeutic strategy. Accordingly, inhibitors of BRDs such as JQ1 have been actively developed and some have reached clinical te...

The bromodomain and extra-terminal inhibitor CPI203 enhances the antiproliferative effects of rapamycin on human neuroendocrine tumors.

Cell Death Dis. 5 , e1450, (2014)

Endogenous c-MYC (MYC) has been reported to be a potential pharmacological target to trigger ubiquitous tumor regression of pancreatic neuroendocrine tumors (PanNETs) and lung tumors. Recently inhibit...

PFI-3
PFI 4
Propane,1,1-bis(ethylsulfonyl)-2-methyl-
Pyridinium, 1- (2-hydroxy[1,1:3,1-terphenyl]-5-yl)-2,4, 6-triphenyl-, perchlorate (salt)
Cyclohexanecarboxylicacid, 1-methyl-3-oxo-, ethyl ester
2-[1-(2-hydroxy-3,5-dimethylphenyl)cyclohexyl]-4,6-dimethylphenol
6-Bromo-5-chloro-2-(difluoromethyl)nicotinonitrile
2-Chloro-3-(2,3,6-trichlorophenyl)isonicotinaldehyde
4-(Difluoromethyl)-5,6-difluoropyridine-2-sulfonamide
2,6-Dibromo-3-fluorobenzonitrile
Ethyl 1-benzyl-1H-benzo[d][1,2,3]triazole-5-carboxylate
3-(Difluoromethyl)-5-(hydroxymethyl)-4-methoxypicolinonitrile
6-Bromo-2-(difluoromethyl)-5-nitronicotinic acid
2-Chloro-6-(difluoromethyl)-3-methylisonicotinic acid
2,4-Dichloro-5-(2,5-dichlorophenyl)pyrimidine
2-(6-Chloro-4-(difluoromethyl)-5-fluoropyridin-3-yl)acetic acid

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