PFI-1
Suppliers
Names
[ CAS No. ]:
1403764-72-6
[ Name ]:
PFI-1
[Synonym ]:
2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydro-6-quinazolinyl)benzenesulfonamide
Benzenesulfonamide, 2-methoxy-N-(1,2,3,4-tetrahydro-3-methyl-2-oxo-6-quinazolinyl)-
QCR-192
PFI-1
CS-1362
PF-6405761
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Molecular Formula ]:
C16H17N3O4S
[ Molecular Weight ]:
347.389
[ Exact Mass ]:
347.093964
[ PSA ]:
96.12000
[ LogP ]:
0.53
[ Appearance of Characters ]:
white to beige
[ Index of Refraction ]:
1.628
[ Storage condition ]:
2-8°C
[ Water Solubility ]:
DMSO: ≥10mg/mL
MSDS
Safety Information
[ RIDADR ]:
NONH for all modes of transport
Articles
Oncotarget 6 , 34669-79, (2015)
Inhibition of BET bromodomains (BRDs) has emerged as a promising cancer therapeutic strategy. Accordingly, inhibitors of BRDs such as JQ1 have been actively developed and some have reached clinical te...
Cell Death Dis. 5 , e1450, (2014)
Endogenous c-MYC (MYC) has been reported to be a potential pharmacological target to trigger ubiquitous tumor regression of pancreatic neuroendocrine tumors (PanNETs) and lung tumors. Recently inhibit...