Olopatadine Hydrochloride

Suppliers

Names

[ Name ]:
Olopatadine Hydrochloride

[Synonym ]:
AL 4943A
MFCD00875716
Olopatadine hydrochloride
Dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, (11Z)-, hydrochloride (1:1)
{(11Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenzo[b,e]oxepin-2-yl}acetic acid hydrochloride
{(11Z)-11-[3-(Dimethylamino)propyliden]-6,11-dihydrodibenzo[b,e]oxepin-2-yl}essigsäurehydrochlorid
{(11Z)-11-[3-(Dimethylamino)propylidene]-6,11-dihydrodibenzo[b,e]oxepin-2-yl}acetic acid hydrochloride (1:1)
dibenz[b,e]oxepin-2-acetic acid, 11-[3-(dimethylamino)propylidene]-6,11-dihydro-, (11Z)-, hydrochloride
acide {(11Z)-11-[3-(diméthylamino)propylidène]-6,11-dihydrodibenzo[b,e]oxépin-2-yl}acétique chlorhydrate
Olopatadine (hydrochloride)

Chemical & Physical Properties

[ Density]:
1.221 g/cm3

[ Boiling Point ]:
523ºC at 760mmHg

[ Melting Point ]:
242-245ºC

[ Molecular Formula ]:
C₂₁H₂₄ClNO₃

[ Molecular Weight ]:
373.873

[ Flash Point ]:
270.1ºC

[ Exact Mass ]:
373.144470

[ PSA ]:
49.77000

[ LogP ]:
4.39150

[ Vapour Pressure ]:
9.65E-13mmHg at 25°C

[ Storage condition ]:
Refrigerator

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H400

[ Precautionary Statements ]:
P273-P301 + P310

[ Hazard Codes ]:
T,N

[ Risk Phrases ]:
25-50

[ Safety Phrases ]:
45-61

[ RIDADR ]:
UN 2811 6.1 / PGIII

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

(11-oxo-6,11-dihydro-dibenzo[b,e]oxepin-2-yl)-acetic acid benzyl ester
(3-(Dimethylamino)propyl)triphenylphosphonium bromide hydrobromide
Olopatadine
olopatadine
magnesium,N,N-dimethylpropan-1-amine,chloride
Isoxepac
(Z)-11-[3-(dimethylamino)propylidene]-6,11-dihydrodibenz[b,e]oxepin-2-acetic acid methyl ester
(Z)-11-(3-dimethylaminopropylidene)-6,11-dihydrodibenz[b,e] oxepin-2-acetic acid ethyl ester
3-Chloro-N,N-dimethylpropan-1-amine

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

Topical cyclosporine a 1% for the treatment of chronic ocular surface inflammation.

Eye Contact Lens 40(5) , 283-8, (2014)

To evaluate the use of topical cyclosporine A (CsA) 1% emulsion in the treatment of chronic ocular surface inflammation (OSI).We conducted a retrospective chart review of patients with various forms o...

Histamine suppresses regulatory T cells mediated by TGF-β in murine chronic allergic contact dermatitis.

Exp. Dermatol. 24(4) , 280-4, (2015)

Regulatory T cells (Tregs) suppress effector T cells and ameliorate contact hypersensitivity (CH); however, the role of Tregs in chronic allergic contact dermatitis (CACD) has not been assessed. Repea...

Chromatographic analysis of olopatadine in hydrophilic interaction liquid chromatography.

J. Chromatogr. Sci. 53 , 680-6, (2015)

In this paper, chromatographic analysis of active substance olopatadine hydrochloride, which is used in eye drops as antihistaminic agent, and its impurity E isomer by hydrophilic interaction liquid c...

olopatadine hydrochloride
(E)-Olopatadine Hydrochloride
2-[11-[3-[bis(trideuteriomethyl)amino]propylidene]-6H-benzo[c][1]benzoxepin-2-yl]acetic acid,hydrochloride
Olopatadine-d3 (hydrochloride)
Olopatadine Isopropyl ester Hydrochloride
Olopatadine Methanol
3,5-Dichloro-4-pyridinone
Phenol, 3,4-dimethoxy-, 1-(N-methylcarbamate)
3-Oxo-4-(4-methoxyphenyl)butanoic acid
n-Propyl-4-piperidinamine
2-((6-(2-methylbenzyl)-5,5-dioxido-6H-benzo[c]pyrimido[4,5-e][1,2]thiazin-2-yl)thio)-N-phenylacetamide
4-(Hexylamino)pentan-1-ol
4-Nitro-1H-pyrrole-3-carbaldehyde
1H-Pyrrole-2-carbonitrile, 1-(3-chloro-2-propenyl)-4-formyl-, (E)-
2-Mercapto-3-(trifluoromethyl)aniline
3aH,4H,5H,6aH-furo[3,2-d][1,2]oxazole

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.