Gramicidin TFA

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Names

[ Name ]:
Gramicidin TFA

[Synonym ]:
GRAMICIDIN (gramicidin A shown)
N-Formyl-L-valylglycyl-L-alanyl-D-leucyl-L-alanyl-D-valyl-L-valyl-D-valyl-L-tryptophyl-D-leucyl-L-tryptophyl-D-leucyl-L-tryptophyl-D-leucyl-N-(2-hydroxyethyl)-L-tryptophanamide
L-Tryptophanamide, N-formyl-L-valylglycyl-L-alanyl-D-leucyl-L-alanyl-D-valyl-L-valyl-D-valyl-L-tryptophyl-D-leucyl-L-tryptophyl-D-leucyl-L-tryptophyl-D-leucyl-N-(2-hydroxyethyl)-
GRAMICIDINE
GRAMICIDIN

Chemical & Physical Properties

[ Melting Point ]:
229-230℃

[ Molecular Formula ]:
C₉₉H₁₄₀N₂₀O₁₇

[ Molecular Weight ]:
1882.29000

[ Exact Mass ]:
1881.07000

[ PSA ]:
548.99000

[ LogP ]:
11.26260

[ Vapour Pressure ]:
0mmHg at 25°C

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
Practically insoluble in water, soluble in methanol, sparingly soluble in alcohol | Soluble in acetic acid and lower alcohols. Practically insoluble in water.

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
20/21-36/37/38

[ Safety Phrases ]:
26-36-24/25-22

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
MD8225000

Articles

Unsaturated lipids protect the integral membrane peptide gramicidin A from singlet oxygen

FEBS Lett. 588(9) , 1590-5, (2014)

• Unsaturated lipids protect gramicidin channels from photosensitized inactivation. • Photosensitizer binding to membrane is independent of lipid unsaturation. • Double bonds in lipids reduce gramicid...

The contribution of raised intraneuronal chloride to epileptic network activity.

J. Neurosci. 35 , 7715-26, (2015)

Altered inhibitory function is an important facet of epileptic pathology. A key concept is that GABAergic activity can become excitatory if intraneuronal chloride rises. However, it has proved difficu...

Inversion of membrane surface charge by trivalent cations probed with a cation-selective channel.

Langmuir 28(45) , 15824-30, (2012)

We demonstrate that the cation-selective channel formed by gramicidin A can be used as a reliable sensor for studying the multivalent ion accumulation at the surfaces of charged lipid membranes and th...

Gramicidin C
Gramicidin S, 5-(N5-acetyl-L-ornithine)- 10
gramicidin A, Leu(2)-
gramicidin A, Leu(5)-
Gramicidin A
GRAMICIDIN S HYDROCHLORIDE
N-ethyl-2,4-dimethylpyrrolo[1,2-a]pyrimidine-8-sulfonamide
2-(Thiophen-2-yl)-4H-benzo[4,5]imidazo[2,1-b][1,3]thiazin-4-one
4-((Cyclohexylamino)methyl)benzoic acid hydrochloride
1-[(2,4-Dichlorophenyl)methyl]-N-(1,1-dimethylethyl)-2-methyl-1H-indole-3-methanamine
2-Methoxy-6-(pyrazol-1-yl)-benzonitrile
N-(2-methoxyethyl)-octahydro-1H-2-benzopyran-6-amine
2-[1-(2,3,4-Trifluorophenyl)cyclobutyl]ethan-1-amine
2-{1-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-1,3-thiazole-4-carbonyl]piperidin-3-yl}acetic acid
4-(2-bromoethenyl)-1-(2-methoxyethyl)-1H-pyrazole
5-fluoro-2-[5-(1-methyl-1H-1,2,3-triazole-4-carbonyl)-octahydropyrrolo[3,4-c]pyrrol-2-yl]pyridine