1,2,3,4-tetrahydroisoquinoline hydrochloride
Suppliers
Names
[ CAS No. ]:
14099-81-1
[ Name ]:
1,2,3,4-tetrahydroisoquinoline hydrochloride
[Synonym ]:
1,2,3,4-tetrahydroisoquinoline,hydrochloride
1,2,3,4-Tetrahydroisoquinoline hydrochloride (1:1)
1,2,3,4-Tetrahydroisoquinoline Hydrochloride
Isoquinoline, 1,2,3,4-tetrahydro-, hydrochloride (1:1)
Isoquinoline 1,2,3,4-tetrahydro, hydrochloride (1:1)
MFCD00012740
1,2,3,4-tetrahydro-isoquinoline HCL
Chemical & Physical Properties
[ Density]:
1.006g/cm3
[ Boiling Point ]:
232.5ºC at 760mmHg
[ Melting Point ]:
198-202 °C
[ Molecular Formula ]:
C9H12ClN
[ Molecular Weight ]:
169.651
[ Flash Point ]:
98.9ºC
[ Exact Mass ]:
169.065826
[ PSA ]:
12.03000
[ LogP ]:
2.46310
[ Vapour Pressure ]:
0.0588mmHg at 25°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- NX5075000
- CHEMICAL NAME :
- Isoquinoline, 1,2,3,4-tetrahydro-, hydrochloride
- CAS REGISTRY NUMBER :
- 14099-81-1
- LAST UPDATED :
- 199012
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C9-H11-N.Cl-H
- MOLECULAR WEIGHT :
- 169.67
- WISWESSER LINE NOTATION :
- T66 CNT&J &GH
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 303 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 18,1194,1975
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Parenteral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 230 mg/kg
- TOXIC EFFECTS :
- Behavioral - rigidity (including catalepsy) Behavioral - muscle contraction or spasticity Skin and Appendages - hair
- REFERENCE :
- JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 62,165,1938
Safety Information
[ Hazard Codes ]:
Xn: Harmful;Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S36/37/39-S26-S37/39
[ RTECS ]:
NX5075000
[ HS Code ]:
2933499090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933499090
[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%