Sodium formate

Names

[ CAS No. ]:
141-53-7

[ Name ]:
Sodium formate

[Synonym ]:
Formic acid,sodium salt
Sodium formate
EINECS 205-488-0
Formic acid sodium salt
MFCD00013101

Chemical & Physical Properties

[ Density]:
1.16 g/mL at 20 °C

[ Boiling Point ]:
360 °C

[ Melting Point ]:
259-262 °C(lit.)

[ Molecular Formula ]:
CHNaO₂

[ Molecular Weight ]:
68.007

[ Flash Point ]:
29.9ºC

[ Exact Mass ]:
67.987427

[ PSA ]:
40.13000

[ Vapour Pressure ]:
36.5mmHg at 25°C

[ Storage condition ]:
2-8°C

[ Stability ]:
Stable. Incompatible with strong oxidizing agents, strong acids. Protect from moisture.

[ Water Solubility ]:
Soluble

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LR0350000

CHEMICAL NAME :: Formic acid, sodium salt

CAS REGISTRY NUMBER :: 141-53-7

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C-H-O2.Na

MOLECULAR WEIGHT :: 68.01

WISWESSER LINE NOTATION :: VHO &-NA-

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 11200 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ZERNAL Zeitschrift fuer Ernaehrungswissenschaft. (Dr. Dietrich Steinkopff Verlag, Postfach 111008, D-6100 Darmstadt 11, Fed. Rep. Ger.) V.1- 1960- Volume(issue)/page/year: 9,332,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 807 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ZERNAL Zeitschrift fuer Ernaehrungswissenschaft. (Dr. Dietrich Steinkopff Verlag, Postfach 111008, D-6100 Darmstadt 11, Fed. Rep. Ger.) V.1- 1960- Volume(issue)/page/year: 9,332,1969

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Unreported

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BJCAAI British Journal of Cancer. (Macmillan Press Ltd., Houndmills, Basingstoke, Hants. RG21 2XS, UK) V.1- 1947- Volume(issue)/page/year: 6,160,1952

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 16,463,1921

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 16,463,1921

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 1140 mg/kg

TOXIC EFFECTS :: Behavioral - sleep Behavioral - somnolence (general depressed activity) Behavioral - muscle weakness

REFERENCE :: AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 21,119,1886

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 1250 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - miosis (pupillary constriction) Autonomic Nervous System - other (direct) parasympathomimetic Kidney, Ureter, Bladder - urine volume increased

REFERENCE :: AEXPBL Archiv fuer Experimentelle Pathologie und Pharmakologie. (Leipzig, Ger. Dem. Rep.) V.1-109, 1873-1925. For publisher information, see NSAPCC. Volume(issue)/page/year: 21,119,1886 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 81986 No. of Facilities: 707 (estimated) No. of Industries: 20 No. of Occupations: 24 No. of Employees: 5113 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 81986 No. of Facilities: 1141 (estimated) No. of Industries: 24 No. of Occupations: 36 No. of Employees: 18895 (estimated) No. of Female Employees: 6339 (estimated)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H319-H336

[ Precautionary Statements ]:
P280-P304 + P340 + P312-P305 + P351 + P338-P337 + P313

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

[ RTECS ]:
LR0350000

[ HS Code ]:
2915120000

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

4-AMino-5-(forMaMidoMethyl)-2-MethylpyriMidine
Carbon dioxide
Propylene Glycol
Formaldehyde
Formic Acid
ch3cho
Hydrogen
SodiuM bicarbonate
sodium,methyl carbonate

DownStream

7-Methylbenzo[d]oxazole
[2-(4-bromophenyl)-2-oxoethyl] formate
3-Hydroxy-4-methoxybenzonitrile
3-Pyrrolidinecarboxylic Acid
Glycine
H-DL-Pro-OH
D-methionine
5-methyl-6-phenylthieno[2,3-d]pyrimidin-4-ol
2-hydroxycyclooctan-1-one
2-Propenoic acid,3-phenyl-, 1,1'-anhydride

Customs

[ HS Code ]: 2915120000

[ Summary ]:
2915120000 salts of formic acid。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

Articles

Crystal structures and kinetics of Type III 3-phosphoglycerate dehydrogenase reveal catalysis by lysine.

FEBS J. 281(24) , 5498-512, (2014)

D-Phosphoglycerate dehydrogenase (PGDH) catalyzes the first committed step of the phosphorylated serine biosynthesis pathway. Here, we report for the first time, the crystal structures of Type IIIK PG...

Hysteresis in human UDP-glucose dehydrogenase is due to a restrained hexameric structure that favors feedback inhibition.

Biochemistry 53(51) , 8043-51, (2014)

Human UDP-α-d-glucose-6-dehydrogenase (hUGDH) displays hysteresis because of a slow isomerization from an inactive state (E*) to an active state (E). Here we show that the structure of E* constrains h...

Detoxification of biomass hydrolysates with nucleophilic amino acids enhances alcoholic fermentation.

Bioresour. Technol. 186 , 106-13, (2015)

Carbonyl compounds generated in biomass pretreatment hinder the biochemical conversion of biomass hydrolysates to biofuels. A novel approach of detoxifying hydrolysates with amino acids for ethanol pr...

Sodium formate
Sodium formate
Sodium formate
Sodium formate
sodium formate
Sodium formate-12C
2-(Difluoromethyl)-3-fluoro-6-hydroxypyridine-5-carboxylic acid
2-(Difluoromethyl)-4-hydroxy-3-methylpyridine-6-acetonitrile
2-(Difluoromethyl)-4-hydroxy-5-nitro-3-(trifluoromethyl)pyridine
2-(Difluoromethyl)-4-hydroxy-3-(trifluoromethoxy)pyridine-6-methanol
2-(Difluoromethyl)-4-hydroxy-6-methoxypyridine
2-(Difluoromethyl)-4-hydroxy-5-nitropyridine-3-carbonyl chloride
2-(Difluoromethyl)-3-hydroxy-5-(trifluoromethyl)pyridine-6-carboxylic acid
2-(Difluoromethyl)-4-iodo-3-nitropyridine
2-(Difluoromethyl)-4-hydroxy-6-iodo-3-nitropyridine
2-(Difluoromethyl)-4-iodo-3-methoxy-5-(trifluoromethyl)pyridine

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